Center of Medical and Health Research, University of Málaga, Málaga, Spain,
Department of Nursing, University Hospital of Ceuta, Ceuta, Spain.
Dement Geriatr Cogn Disord. 2020;49(1):107-120. doi: 10.1159/000508626. Epub 2020 Jul 7.
In the last three decades, the relationship between depression and cognition in geriatric patients has been a popular topic among researchers and clinicians. Clinical and epidemiological research has focused on the identification of risk factors that could be modified in pre-dementia syndromes, at a preclinical and early clinical stage of dementia disorders, with specific attention to the role of depression. The objective of this work was to determine the relationship between depressive disorder and cognitive deterioration in institutionalized older adults.
In this descriptive, correlational study, data were gathered from two nursing homes in the province of Jaen (Spain), from a random sample of 140 older adults (70 nondependent and 70 dependent). The variables were measured using comprehensive geriatric assessment, the Cambridge Cognitive Test (CAMCOG), and the Geriatric Depression Scale (GDS).
Depression was correlated with cognitive level in the nondependent older adult sample (r = -0.471, p = 0.004). Age was inversely associated with the score obtained in the CAMCOG of the nondependent older adult sample (r = -0.352, p = 0.038). The functional capacity in several activities of daily living was correlated with the score obtained in the CAMCOG in each of the two groups. Depression was more prevalent in the dependent than in the nondependent older adults (82.85 vs. 57.14%). No association was observed between institutionalization time and the score obtained on the cognitive and affective scales (GDS and CAMCOG) in both groups (GDS-nondependent, r = -0.209, p = 0.234; CAMCOG-nondependent, r = 0.007, p = 0.967; GDS-dependent, r = 0.251, p = 0.152; CAMCOG-dependent, r = -0.021, p = 0.907).
Depressive symptomatology is associated with cognitive deterioration. Depression is prevalent in institutions that care for older, more dependent adults.
在过去的三十年中,老年患者的抑郁与认知之间的关系一直是研究人员和临床医生关注的热门话题。临床和流行病学研究的重点是确定可在痴呆前综合征、痴呆症早期临床阶段进行修改的风险因素,特别关注抑郁的作用。本研究的目的是确定抑郁障碍与机构化老年患者认知能力下降之间的关系。
在这项描述性、相关性研究中,数据来自西班牙哈恩省的两家养老院,从一个随机样本中抽取了 140 名老年人(70 名非依赖者和 70 名依赖者)。使用综合老年评估、剑桥认知测验(CAMCOG)和老年抑郁量表(GDS)测量变量。
抑郁与非依赖组老年人的认知水平相关(r=-0.471,p=0.004)。年龄与非依赖组老年人的 CAMCOG 评分呈负相关(r=-0.352,p=0.038)。日常生活活动中的几种功能能力与两组的 CAMCOG 评分相关。依赖组的老年人比非依赖组的老年人更易患抑郁(82.85%比 57.14%)。在两组中,机构化时间与认知和情感量表(GDS 和 CAMCOG)的评分之间均无关联(GDS-非依赖,r=-0.209,p=0.234;CAMCOG-非依赖,r=0.007,p=0.967;GDS-依赖,r=-0.251,p=0.152;CAMCOG-依赖,r=-0.021,p=0.907)。
抑郁症状与认知能力下降有关。抑郁在照顾年龄较大、依赖性较强的老年人的机构中较为普遍。