Malone Janna, Gaviolli Eduardo, Doody Janice, Sinclair John, Malone Shawn
Radiation Oncology, The Ottawa Hospital, Ottawa, CAN.
Medicine, McMaster University, Hamilton, CAN.
Cureus. 2020 Jun 2;12(6):e8409. doi: 10.7759/cureus.8409.
Meningiomas are tumors that originate from the meningeal or dural cover of the brain and are the most common primary benign brain tumors. Currently, the accepted management of these tumors is attempted total surgical excision when technically possible and associated with an acceptable risk. However, radiation therapy has been shown to provide excellent local control when used either as an adjunct to surgery or as a primary treatment. We present a case report of a 46-year-old female patient with an unresectable left foramen magnum meningioma resulting in headaches, neck pain, and swallowing difficulty. The patient underwent CyberKnife (Accuray Incorporated, Sunnyvale, CA) radiosurgery to a dose of 3,000 cGy in five fractions in March 2011. The patient tolerated treatment without complications and has remained clinically well with no ongoing cranial nerve deficits as of the last examination in late 2019. This demonstrates the excellent local control obtained when using radiosurgery as both a surgical adjunct and a primary treatment for meningiomas.
脑膜瘤是起源于脑膜或脑硬膜的肿瘤,是最常见的原发性良性脑肿瘤。目前,对于这些肿瘤,公认的治疗方法是在技术可行且风险可接受的情况下尝试进行全手术切除。然而,放射治疗已被证明,无论是作为手术辅助手段还是作为主要治疗方法,都能提供出色的局部控制效果。我们报告一例46岁女性患者,患有无法切除的左枕骨大孔脑膜瘤,导致头痛、颈部疼痛和吞咽困难。该患者于2011年3月接受了射波刀(Accuray Incorporated,加利福尼亚州桑尼维尔)放射外科治疗,分五次给予3000 cGy的剂量。患者耐受治疗且无并发症,截至2019年末的最后一次检查,临床状况良好,无持续的颅神经缺损。这证明了将放射外科作为脑膜瘤的手术辅助手段和主要治疗方法时可获得出色的局部控制效果。