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全肘关节翻修术中超高相对分子量聚乙烯的定量磨损。

Quantitative ultrahigh-molecular-weight polyethylene wear in total elbow retrievals.

机构信息

Implant Research Center, School of Biomedical Engineering, Science, and Health Systems, Drexel University, Philadelphia, PA, USA; Exponent, Inc., Philadelphia, PA, USA.

Implant Research Center, School of Biomedical Engineering, Science, and Health Systems, Drexel University, Philadelphia, PA, USA.

出版信息

J Shoulder Elbow Surg. 2020 Nov;29(11):2364-2374. doi: 10.1016/j.jse.2020.03.026. Epub 2020 Jun 9.

Abstract

BACKGROUND

The purpose of this study was to evaluate ultrahigh-molecular-weight polyethylene (UHMWPE) wear and damage from retrieved total elbow arthroplasty components and compare in vivo wear with wear produced in vitro.

METHODS

Explanted total elbow components were collected at revision surgery. UHMWPE damage was characterized visually, whereas penetration and wear were quantified using micro-computed tomography and gas pycnometry. Volumetric wear rates were compared with historical hip data, and wear data were compared with reported in vitro wear test data.

RESULTS

Humeral bushing damage primarily occurred in the form of burnishing, scratching, and pitting at the articular face in the region of contact with the ulnar component. Wear of the ulnar bushings was concentrated on the edge of the component at the point of contact with the axis pin. Pitting and embedded debris were dominant damage modes, in addition to burnishing and delamination. Backside wear was negligible. The median linear penetration rates of the lateral, medial, and ulnar bushings were 0.14 mm/yr (range, 0.01-0.78 mm/yr), 0.12 mm/yr (range, 0.03-0.55 mm/yr), and 0.11 mm/yr (range, 0.01-0.69 mm/yr), respectively. The volumetric wear rates of the lateral, medial, and ulnar bushings were 5.5 mm/yr (range, 0.7-37.2 mm/yr), 5.9 mm/yr (range, 0.6-25.5 mm/yr), and 5.5 mm/yr (range, 1.2-51.2 mm/yr), respectively.

CONCLUSIONS

The observed wear rates were similar to those reported in well-functioning total hip replacement patients with conventional UHMWPE bearings. We found limitations in reported in vitro testing resulting in wear that was not consistent with our retrieval data. We recommend further investigation to clinically validate in vitro simulation to provide appropriate loading protocols for elbow wear simulation.

摘要

背景

本研究旨在评估全肘假体中超高相对分子量聚乙烯(UHMWPE)的磨损和损伤情况,并对体内和体外磨损进行比较。

方法

在翻修手术时收集全肘置换组件。采用微计算机断层扫描和气体比重瓶对 UHMWPE 损伤进行定性描述,对穿透和磨损进行定量检测。将体积磨损率与髋关节的历史数据进行比较,并将磨损数据与报告的体外磨损试验数据进行比较。

结果

肱骨衬垫的损伤主要表现为关节面处的打磨、划伤和点蚀,这些损伤主要位于与尺骨组件接触的区域。尺骨衬垫的磨损主要集中在与轴销接触的组件边缘处。除了打磨和分层外,点蚀和嵌入的碎屑是主要的损伤模式。背面磨损可忽略不计。外侧、内侧和尺骨衬套的中位线性穿透率分别为 0.14 mm/yr(范围 0.01-0.78 mm/yr)、0.12 mm/yr(范围 0.03-0.55 mm/yr)和 0.11 mm/yr(范围 0.01-0.69 mm/yr)。外侧、内侧和尺骨衬套的体积磨损率分别为 5.5 mm/yr(范围 0.7-37.2 mm/yr)、5.9 mm/yr(范围 0.6-25.5 mm/yr)和 5.5 mm/yr(范围 1.2-51.2 mm/yr)。

结论

观察到的磨损率与常规 UHMWPE 轴承的全髋关节置换患者中报告的磨损率相似。我们发现报告的体外试验存在局限性,导致磨损与我们的检索数据不一致。我们建议进一步研究以验证体外模拟的临床相关性,为肘部磨损模拟提供适当的加载方案。

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