Gynecology and Breast Care Unit, Mater Olbia Hospital, Olbia, Italy.
Division of Gynecologic Oncology, Gemelli Molise, Campobasso, Italy.
Arch Gynecol Obstet. 2020 Oct;302(4):983-993. doi: 10.1007/s00404-020-05694-0. Epub 2020 Jul 16.
Segmental resection has been generally associated with increased peri-operative risk of major complications. While major complications are widely acknowledged, minor complications, such as slight, to moderate infections, peripheral sensory disturbances, bladder voiding dysfunction, postoperative urinary obstruction, and sexual disorders are less reported. The aim of this study is to investigate the surgery-related complications and functional disorders, as well as to evaluate their persistence after long-term follow-up in women undergone segmental resection for deep infiltrating endometriosis. Special attention is given to evaluating impairments of bowel, bladder, and sexual function.
All clinical data obtained from medical records of women who underwent segmental resection for intestinal endometriosis between October 2005, and November 2017, in Catholic University Institutions. Perioperative morbidity was classified by Extended Clavien-Dindo classification. Postoperative intestinal, voiding, and sexual morbidity was estimated by the compilation of specific questionnaires.
Fifty women were included in the study. Forty-three high colorectal resections (86%), 6 low resections (12%), and 1 ultra-low resection (2%) were performed, while in 3 cases (6%) multiple resections were needed. The overall complication rate was 44%. Nineteen women (38%) experienced early complications and 3 women (6%) late complications. Long-term functional postoperative complications were composed of intestinal in 30%, urinary in 50%, and sexual in 64% of the study population. Median follow-up was 55.5 months.
Segmental resection, when indicated, offers a radical and feasible approach for bowel deep infiltrating endometriosis, resulting in an improved general quality of life. The bowel and bladder complications appear to be acceptable and often reversible. Postoperative sexual dysfunctions, such as anorgasmia and insufficient vaginal lubrication, appear to persist over time. Surgeons and women have to be aware of the incidence of this kind of complications.
节段切除术通常与围手术期发生重大并发症的风险增加有关。虽然广泛承认重大并发症,但轻微至中度感染、周围感觉障碍、膀胱排空功能障碍、术后尿路梗阻和性功能障碍等轻微并发症的报道较少。本研究旨在探讨接受深部浸润性子宫内膜异位症节段切除术的女性的手术相关并发症和功能障碍,并评估其在长期随访后的持续性。特别关注评估肠、膀胱和性功能障碍。
所有临床数据均来自 2005 年 10 月至 2017 年 11 月在天主教大学机构接受肠内子宫内膜异位症节段切除术的女性的病历。围手术期发病率按扩展 Clavien-Dindo 分类进行分类。通过编制特定问卷评估术后肠道、排尿和性功能障碍。
研究纳入 50 名女性。43 例为高结直肠切除术(86%),6 例为低切除术(12%),1 例超低切除术(2%),3 例(6%)需要多次切除术。总并发症发生率为 44%。19 名女性(38%)出现早期并发症,3 名女性(6%)出现晚期并发症。长期术后功能性并发症包括肠道 30%、泌尿 50%和性 64%的研究人群。中位随访时间为 55.5 个月。
当指征明确时,节段切除术为肠深部浸润性子宫内膜异位症提供了一种根治性且可行的方法,从而提高了整体生活质量。肠道和膀胱并发症似乎可以接受,且通常是可逆的。术后性功能障碍,如性高潮障碍和阴道润滑不足,似乎会随着时间的推移而持续存在。外科医生和女性必须意识到这种并发症的发生率。