Graduate Programs in Human Nutrition, Oregon Health & Science University, Portland, OR, USA.
Graduate Programs in Human Nutrition, Oregon Health & Science University, Portland, OR, USA.
Clin Nutr ESPEN. 2020 Aug;38:99-110. doi: 10.1016/j.clnesp.2020.05.023. Epub 2020 Jun 29.
BACKGROUND & AIMS: Malnutrition is a top priority in Lao PDR. In 2017, 33% of children under five years of age were stunted, 21.1% were underweight, 9% were wasted while 16.6% of adults in community settings were malnourished. Rates of malnutrition are presumed to be higher among hospitalized patients however, malnutrition risk screening in inpatient settings does not occur in Lao PDR. To address this gap, this study aimed to determine the prevalence of malnutrition among hospitalized patients and investigated the inter-user reliability and validity of a nutrition-risk screening tool (NRST).
A cross-sectional study of pediatric (n = 69) and adult (n = 125) patients was conducted at two hospitals in Vientiane, Lao PDR. Inter-observer reliability of the NRST was determined by comparing final scores of two independent observers. Validity of the NRST was determined using sensitivity, specificity, and area-under-the-receiver-operating-characteristics (ROC) curve analyses.
Among participants 0-4 years of age, 51% were diagnosed with malnutrition, while 58% of participants aged 5-17 years were malnourished. Among participants 18 years of age or older, 47% were diagnosed with moderate to severe malnutrition. The NRST showed 'fair' agreement between Observer 1 and Observer 2 NRST final scores (0.2737, p-value <0.001). Observer 1 and Observer 2 had a 64% and 70% probability of correctly distinguishing a malnourished from a not malnourished participant. The Lao NRST had a sensitivity of 85% and a specificity 35%.
There is a high prevalence of malnutrition among hospitalized patients in Lao PDR. This study provides proof of concept that a nutrition-risk screening tool can be successfully administered in a low-resource setting. Timely identification of malnutrition among newly admitted hospitalized patients will help minimize adverse patient health outcomes and reduce the economic burden of healthcare in Lao PDR.
营养不良是老挝人民民主共和国的首要问题。2017 年,5 岁以下儿童中有 33%发育迟缓,21.1%体重不足,9%消瘦,而社区环境中有 16.6%的成年人营养不良。然而,人们认为住院患者中的营养不良率更高,但老挝人民民主共和国的住院患者并未进行营养不良风险筛查。为了解决这一差距,本研究旨在确定住院患者中营养不良的患病率,并研究一种营养风险筛查工具(NRST)的用户间可靠性和有效性。
在老挝万象的两家医院进行了一项儿科(n=69)和成人(n=125)患者的横断面研究。通过比较两名独立观察者的最终评分来确定 NRST 的观察者间可靠性。通过灵敏度、特异性和受试者工作特征(ROC)曲线下面积分析来确定 NRST 的有效性。
在 0-4 岁的参与者中,51%被诊断为营养不良,而 5-17 岁的参与者中 58%营养不良。在 18 岁或以上的参与者中,47%被诊断为中重度营养不良。NRST 显示观察者 1 和观察者 2 的 NRST 最终评分之间存在“中等”一致性(0.2737,p 值<0.001)。观察者 1 和观察者 2 正确区分营养不良和非营养不良参与者的概率分别为 64%和 70%。老挝 NRST 的灵敏度为 85%,特异性为 35%。
老挝住院患者中存在较高的营养不良患病率。本研究证明了营养风险筛查工具可以在资源匮乏的环境中成功实施。及时识别新入院住院患者的营养不良状况,将有助于最大限度地减少患者健康不良后果,并减轻老挝人民民主共和国医疗保健的经济负担。