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摩洛哥西北部成人和儿童脑膜炎的流行病学、细胞化学和细菌学特征。

Epidemiological, Cytochemical and Bacteriological Profile of Meningitis among Adults and Children in North West of Morocco.

出版信息

Pak J Biol Sci. 2020 Jan;23(7):891-897. doi: 10.3923/pjbs.2020.891.897.

Abstract

BACKGROUND AND OBJECTIVE

Meningitis is a medical and public health problem in Morocco, particularly in the North West region. The purpose of present study was to identify the pathogen in pyogenic meningitis and to determine its antibiotic susceptibility pattern Materials and Methods: A total of 247 cases were included in the diagnosis of meningitis on the basis of clinical findings and positive cerebrospinal fluid (CSF).

RESULTS

The study included 247 cases with a mean cumulative incidence of 4.53 (100,000 Hts) meningitis in all forms during the study period. The sex ratio M/F was 1.71. Maximum numbers of cases were<15 year of age, 139 (56.3%). Bacterial meningeal syndrome was observed in 67.2% of cases. Cerebrospinal fluid (CSF) was cloudy in 57.1% of cases. The average number of GBs was 1074.12 (±2115.63) elements mm-3. Mean glycorrhachia was 0.48 g L-1 (±0.28) and mean protein levels were 1.5 g L-1 (±1.68). The common pathogens identified on CSF culture were coagulase, negative Neisseria meningitidis in 30 (13%) and Streptococcus pneumoniae 6 (2.5%). Overall mortality was 14.9%.

CONCLUSION

Hence, Meningitis is a real health problem in the province of Kenitra, affecting especially children. Effective involvement of all health personnel and the community fight this epidemic disease.

摘要

背景与目的

脑膜炎是摩洛哥的一个医学和公共卫生问题,尤其是在西北部地区。本研究的目的是确定化脓性脑膜炎的病原体,并确定其抗生素敏感性模式。

材料与方法

根据临床发现和脑脊液(CSF)阳性,共有 247 例被诊断为脑膜炎。

结果

本研究共纳入 247 例患者,在研究期间所有形式的脑膜炎累积发病率平均为 4.53(100,000 Hts)。男女比例为 1.71。最大数量的病例为<15 岁,139 例(56.3%)。67.2%的病例表现为细菌性脑膜综合征。57.1%的病例脑脊液(CSF)混浊。平均革兰氏染色数为 1074.12(±2115.63)个/mm-3。平均糖水平为 0.48 g L-1(±0.28),平均蛋白水平为 1.5 g L-1(±1.68)。在 CSF 培养中鉴定出的常见病原体是凝固酶阴性脑膜炎奈瑟菌和肺炎链球菌,分别为 30 例(13%)和 6 例(2.5%)。总死亡率为 14.9%。

结论

因此,脑膜炎是肯尼特拉省的一个真正的健康问题,特别是对儿童的影响。有效动员所有卫生人员和社区参与防治这种传染病。

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