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心力衰竭中的神经调节疗法:药物与设备的联合应用

Neuromodulation Therapy in Heart Failure: Combined Use of Drugs and Devices.

作者信息

Sobowale Christopher O, Hori Yuichi, Ajijola Olujimi A

机构信息

UCLA Cardiac Arrhythmia Center, UCLA Neurocardiology Research Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

Department of Cardiology, Dokkyo Medical University Saitama Medical Center, Saitama, Japan.

出版信息

J Innov Card Rhythm Manag. 2020 Jul 15;11(7):4151-4159. doi: 10.19102/icrm.2020.110705. eCollection 2020 Jul.

Abstract

Heart failure (HF) is the fastest-growing cardiovascular disease globally. The autonomic nervous system plays an important role in the regulation and homeostasis of cardiac function but, once there is HF, it takes on a detrimental role in cardiac function that makes it a rational target. In this review, we cover the remodeling of the autonomic nervous system in HF and the latest treatments available targeting it.

摘要

心力衰竭(HF)是全球增长最快的心血管疾病。自主神经系统在心脏功能的调节和稳态中发挥着重要作用,但一旦发生心力衰竭,它就会对心脏功能产生有害作用,这使其成为一个合理的治疗靶点。在本综述中,我们涵盖了心力衰竭中自主神经系统的重塑以及针对该系统的最新可用治疗方法。

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