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[老年人心脏瓣膜病]

[Valvular heart diseases in the aged].

作者信息

Ohkawa S

机构信息

Division of Cardiology, Tokyo Metropolitan Geriatric Hospital.

出版信息

J Cardiol Suppl. 1988;19:29-38.

PMID:3274212
Abstract

A total of 458 cases (11.5%) with valvular heart diseases in the aged (greater than or equal to 60 years) were found among 4,000 consecutive autopsies. They included 204 cases (45%) of aortic regurgitation (AR), 171 cases (37%) of mitral regurgitation (MR), followed by 45 (10%) of aortic stenosis (AS) and 27 cases (6%) of mitral stenosis (MS). As an etiology of the valvular diseases, degenerative type was found in 195 cases (43%), ischemic origin in 91 cases (20%), followed by inflammatory origin such as syphilitic in 51 and infective endocarditis in three, aortitis in two and rheumatic in 49 (11%). Congenital origin was also found in 18 cases (4%). Among various types of valvular diseases in the aged, degenerative AR was most frequently found in 140 cases, followed by MR due to papillary muscle dysfunction in 91 cases. The clinical characteristics in cases with valvular diseases were as follows: atrial fibrillation was prominent in MS; congestive heart failure was found in 60% of cases except those with degenerative AR; cardiac death was frequent in syphilitic and rheumatic AR; association of hypertension was found in 50% of cases with MR and degenerative AR. In this article the characteristics of the valvular heart disease in the aged and additionally its diagnosis and treatment were discussed.

摘要

在4000例连续尸检中,共发现458例(11.5%)老年(≥60岁)瓣膜性心脏病患者。其中包括204例(45%)主动脉瓣反流(AR)、171例(37%)二尖瓣反流(MR),其次是45例(10%)主动脉瓣狭窄(AS)和27例(6%)二尖瓣狭窄(MS)。作为瓣膜病的病因,退行性类型有195例(43%),缺血性起源91例(20%),其次是炎症性起源,如梅毒51例、感染性心内膜炎3例、主动脉炎2例、风湿性49例(11%)。先天性起源也有18例(4%)。在老年各种类型的瓣膜病中,退行性AR最常见,有140例,其次是因乳头肌功能障碍导致的MR 91例。瓣膜病患者的临床特征如下:MS中房颤突出;除退行性AR外,60%的病例有充血性心力衰竭;梅毒和风湿性AR中心脏性死亡常见;50%的MR和退行性AR病例伴有高血压。本文讨论了老年瓣膜性心脏病的特点及其诊断和治疗。

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