School of Pharmaceutics Education and Research (SPER), Jamia Hamdard, New Delhi, India.
Sun Pharma, R&D Center, Sarhaul, Gurugram-122015, India.
Endocr Metab Immune Disord Drug Targets. 2020;20(10):1624-1636. doi: 10.2174/1871530320666200730225830.
Cessation of menstruation, widely known as menopause is a significant transition period in women's life. It leads to the arrest of fertility and creates a depletion of the hormones causing physical, mental, sexual, and social problems which lead to a serious decline in their quality of life. The onset of menopause induces certain sudden changes, while others appear in a phasic manner, henceforth demanding an adequate understanding of its progression, adverse impact on life, and exploration of any remedial measures thereof. Menopause, despite being a natural occurrence, brings in significant changes to women's life, almost sometimes leading to severe debilitation. However, it is still not attended and remains an ignored health issue that warrants the immediate attention of researchers, practitioners, and health policymakers. The present review is an attempt to draw attention towards these women-centric health issues and diligently explores the causes, symptoms and also describes the various procedures for the management of menopausal and postmenopausal syndromes. The review tries to summarise the currently available pharmaceutical interventions and also dwells into herbal and complementary remedies which could ameliorate and provide respite from the etiolating menopausal symptoms.
绝经,俗称更年期,是女性生命中的一个重要过渡阶段。它导致生育能力停止,并导致激素耗竭,从而导致身体、心理、性和社会问题,导致生活质量严重下降。绝经的发生会引起某些突然的变化,而其他变化则呈阶段性出现,因此需要充分了解其进展、对生活的不利影响以及探索任何补救措施。尽管绝经是一种自然现象,但它会给女性的生活带来重大变化,有时甚至会导致严重的衰弱。然而,它仍然没有得到关注,仍然是一个被忽视的健康问题,需要研究人员、从业者和卫生政策制定者的立即关注。本综述试图引起人们对这些以女性为中心的健康问题的关注,并努力探讨绝经和绝经后综合征的原因、症状,以及描述各种管理方法。该综述试图总结目前可用的药物干预措施,并深入研究草药和补充疗法,这些疗法可以缓解和减轻更年期症状的恶化。