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Fahr 综合征和甲状旁腺功能减退的神经临床特征。

Neurologic Clinical Manifestations of Fahr Syndrome and Hypoparathyroidism.

机构信息

Department of Neurological Surgery, University of Illinois at Chicago, Chicago, Illinois, USA.

Department of Neurological Surgery, University of Illinois at Chicago, Chicago, Illinois, USA.

出版信息

World Neurosurg. 2020 Dec;144:115-116. doi: 10.1016/j.wneu.2020.07.160. Epub 2020 Jul 31.

Abstract

A 41-year-old female with a history of chronic hypoparathyroidism with Fahr syndrome presented with complaints of weakness and muscle spasticity. Brain imaging demonstrated diffuse intracranial calcifications. In addition, cervical spine imaging revealed extensive calcification along the anterior and posterior cervical vertebral bodies causing multilevel stenosis and cord compression. The patient underwent a multilevel posterior cervical decompression and fusion. Postoperatively, the patient had noted improvement in her upper and lower extremity strength and spasticity. This illustrative case demonstrates rare clinical and radiographic neurologic sequelae of long-standing hypoparathyroidism.

摘要

一位 41 岁女性,患有慢性甲状旁腺功能减退症伴 Fahr 综合征,主诉乏力和肌肉痉挛。脑部影像学检查显示弥漫性颅内钙化。此外,颈椎影像学检查显示颈椎前后椎体广泛钙化,导致多节段狭窄和脊髓压迫。患者接受了多节段颈椎后路减压融合术。术后,患者上肢和下肢力量及痉挛均有改善。本病例提示长期甲状旁腺功能减退症罕见的临床和放射影像学神经系统后遗症。

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