Department of Neuroscience, Uppsala University, 75237 Uppsala, Sweden, Phone: +46 18 471 4779, Fax: +46 18 511 540.
Department of Neuroscience, Uppsala University, Uppsala, Sweden.
Scand J Pain. 2020 Jul 28;20(3):533-543. doi: 10.1515/sjpain-2019-0143.
Background and aims Few studies have reported the long-term impact of chronic pain on health care utilization. The primary aim of this study was to investigate if chronic musculoskeletal pain was associated with health care utilization in the general population in a 21-year follow-up of a longitudinal cohort. The secondary aim was to identify and describe factors that characterize different long-term trajectories of health care utilization. Methods A prospective cohort design with a baseline sample of 2,425 subjects (aged 20-74). Data were collected by self-reported questionnaires, and three time points (1995, 2007, and 2016) were included in the present 21-year follow up study. Data on health care utilization were dichotomized at each time point to either high or low health care utilization. High utilization was defined as >5 consultations with at least one health care provider, or ≥1 consultation with at least 3 different health care providers during the last 12 months. Low health care utilization was defined as ≤5 consultations with one health care provider and <3 consultations with different health care providers. The associations between baseline variables and health care utilization in 2016 were analyzed by multiple logistic regression. Five different trajectories for health care utilization were identified by visual analysis, whereof four of clinical relevance were included in the analyses. Results Baseline predictors for high health care utilization at the 21-year follow-up in 2016 were chronic widespread pain (OR: 3.2, CI: 1.9-5.1), chronic regional pain (OR:1.8, CI: 1.2-2.6), female gender (OR: 2.0, CI: 1.4-3.0), and high age (OR: 1.6, CI:0.9-2.9). A stable high health care utilization trajectory group was characterized by high levels of health care utilization, and a high prevalence of chronic pain at baseline and female gender (n = 23). A stable low health care utilization trajectory group (n = 744) was characterized by low health care utilization, and low prevalence of chronic pain at baseline. The two remaining trajectories were: increasing trajectory group (n = 108), characterized by increasing health care utilization, chronic pain at baseline and female gender, and decreasing trajectory group (n = 107) characterized by decreasing health care utilization despite a stable high prevalence of chronic pain over time. Conclusions The results suggest that chronic pain is related to long-term health care utilization in the general population. Stable high health care utilization was identified among a group characterized by female gender and a report of chronic widespread pain. Implications This cohort study revealed that chronic widespread pain predicted high health care utilization over a 21-year follow-up period. The results indicate the importance of early identification of musculoskeletal pain to improve the management of pain in the long run.
鲜有研究报告慢性疼痛对医疗保健利用的长期影响。本研究的主要目的是在一项对纵向队列进行的 21 年随访中,调查慢性肌肉骨骼疼痛是否与普通人群的医疗保健利用相关。次要目的是确定和描述特征不同的医疗保健利用长期轨迹的因素。
采用前瞻性队列设计,基线样本为 2425 名年龄在 20-74 岁的受试者。数据通过自我报告问卷收集,并在本 21 年随访中包含三个时间点(1995 年、2007 年和 2016 年)。医疗保健利用数据在每个时间点均分为高或低医疗保健利用。高利用定义为过去 12 个月内至少有 5 次就诊,至少有 1 次就诊至少有 3 个不同的医疗保健提供者。低医疗保健利用定义为就诊次数不超过 5 次且就诊于不超过 3 个不同医疗保健提供者。通过多元逻辑回归分析,对基线变量与 2016 年医疗保健利用之间的关系进行了分析。通过直观分析确定了医疗保健利用的五种不同轨迹,其中四种具有临床意义被纳入分析。
2016 年 21 年随访时,高医疗保健利用的基线预测因子为慢性广泛性疼痛(OR:3.2,CI:1.9-5.1)、慢性区域性疼痛(OR:1.8,CI:1.2-2.6)、女性(OR:2.0,CI:1.4-3.0)和高龄(OR:1.6,CI:0.9-2.9)。高医疗保健利用率稳定轨迹组的特征是高医疗保健利用率,基线时慢性疼痛发生率高,且为女性(n=23)。稳定低医疗保健利用率轨迹组(n=744)的特征是低医疗保健利用率,且基线时慢性疼痛发生率低。其余两个轨迹为:上升轨迹组(n=108),其特征是医疗保健利用率上升,基线时存在慢性疼痛和女性,下降轨迹组(n=107),其特征是尽管随着时间的推移慢性疼痛的发生率稳定较高,但医疗保健利用率下降。
结果表明,慢性疼痛与普通人群的长期医疗保健利用有关。在一组以女性和慢性广泛性疼痛报告为特征的人群中,发现了稳定的高医疗保健利用率。
本队列研究表明,慢性广泛性疼痛可预测 21 年随访期间的高医疗保健利用率。结果表明,早期识别肌肉骨骼疼痛对于长期改善疼痛管理至关重要。