Conto-Palomino Nadin Melina, Cabrera-Bueno María Luz, Vargas-Ponce Kenneth Grenis, Rondón-Abuhadba Evelina Andrea, Atamari-Anahui Noé
Servicio de Pediatría, Hospital Nacional Arzobispo Loayza, Lima, Perú. ORCID:0000-0002-3584-0806.
Servicio de Pediatría, Hospital Nacional Arzobispo Loayza, Lima, Perú. ORCID:0000-0002-3465-1739.
Medwave. 2020 Aug 3;20(7):e7984. doi: 10.5867/medwave.2020.07.7984.
There are limited reports of neurological symptoms in the pediatric population with COVID-19. We report a 13-year-old girl with three days of illness characterized by headache, non-explosive vomiting, fever, and sudden-onset sensory disorder associated with difficulty in standing and hemiparesis in limbs without evidence of meningeal signs. Brain tomography revealed diffuse brain edema, and the cerebrospinal fluid study was consistent with a viral infection. COVID-19 was diagnosed based on serology. The patient had an untoward clinical course despite treatment with hydroxychloroquine, azithromycin, and corticosteroids, dying on the third day of hospitalization. Encephalitis in a patient with COVID-19 is not frequently reported in the pediatric population. It should be considered in the differential diagnosis in patients who arrives at the emergency with a sensory disorder or neurological symptomatology in the context of the COVID-19 pandemic.
关于新冠病毒感染的儿科患者出现神经症状的报道有限。我们报告了一名13岁女孩,患病三天,症状包括头痛、非喷射性呕吐、发热以及突发感觉障碍,伴有站立困难和肢体偏瘫,无脑膜刺激征迹象。脑部断层扫描显示弥漫性脑水肿,脑脊液检查结果与病毒感染相符。根据血清学诊断为新冠病毒感染。尽管使用了羟氯喹、阿奇霉素和皮质类固醇进行治疗,该患者的临床病程仍不理想,于住院第三天死亡。新冠病毒感染患者发生脑炎在儿科人群中并不常见。在新冠疫情背景下,对于出现感觉障碍或神经症状而前往急诊的患者,应将其纳入鉴别诊断考虑范围。