Albrecht Hendrik Christian, Trawa Mateusz, Gretschel Stephan
Brandenburg Medical School, Department of General, Visceral and Thoracic Surgery, University Hospital Neuruppin, Neuruppin, Germany.
J Int Med Res. 2020 Aug;48(8):300060520929128. doi: 10.1177/0300060520929128.
Postoperative nutrition via a jejunal tube after major abdominal surgery is usually well tolerated. However, some patients develop nonocclusive mesenteric ischemia (NOMI). This morbid complication has a grave prognosis with a mortality rate of 41% to 100%. Early symptoms are nonspecific, and no treatment guideline is available. We reviewed cases of NOMI at our institution and cases described in the literature to identify factors that impact the clinical course. Among five patients, three had no necrosis and one had segmental necrosis and perforation. These patients recovered with limited resection and decompression of the bowel and abdominal compartment. In one patient with extended bowel necrosis at the time of re-laparotomy, NOMI progressed and the patient died of multiple organ failure. The extent of small bowel necrosis at the time of re-laparotomy is a relevant prognostic factor. Therefore, early diagnosis and treatment of NOMI can improve the prognosis. Clinical symptoms of abdominal distension, cramps and high reflux plus paraclinical signs of leukocytosis, hypotension and computed tomography findings of a distended small bowel with pneumatosis intestinalis and portal venous gas can help to establish the diagnosis. We herein introduce an algorithm for the diagnosis and management of NOMI associated with jejunal tube feeding.
腹部大手术后经空肠管进行术后营养通常耐受性良好。然而,一些患者会发生非闭塞性肠系膜缺血(NOMI)。这种严重并发症预后不良,死亡率为41%至100%。早期症状不具特异性,且尚无治疗指南。我们回顾了我院的NOMI病例以及文献中描述的病例,以确定影响临床病程的因素。五名患者中,三名没有坏死,一名有节段性坏死和穿孔。这些患者通过有限的肠切除和肠减压及腹腔减压得以康复。在一名再次剖腹手术时出现广泛肠坏死的患者中,NOMI病情进展,患者死于多器官功能衰竭。再次剖腹手术时小肠坏死的程度是一个相关的预后因素。因此,NOMI的早期诊断和治疗可改善预后。腹胀、绞痛和高度反流的临床症状加上白细胞增多、低血压等临床旁证以及小肠扩张并伴有肠壁积气和门静脉积气的计算机断层扫描结果有助于确诊。我们在此介绍一种与空肠管喂养相关的NOMI诊断和管理算法。