Department of Surgery and Translational Medicine, University of Florence, General and Endocrine Surgery, Careggi University Hospital Florence, Italy.
Department of Molecular and Developmental Medicine, University of Siena Siena, Italy; Department of Experimental, Clinical and Biomedical Sciences, University of Florence, Obstetrics and Gynecology, Careggi University Hospital Florence, Italy.
Reprod Biomed Online. 2020 Oct;41(4):729-733. doi: 10.1016/j.rbmo.2020.06.008. Epub 2020 Jun 20.
This study aimed to evaluate the presence of superficial peritoneal endometriosis (SUP) in women referred to emergency surgery for right iliac fossa (RIF) pain and undergoing an appendectomy, considering which factors may be useful to suspect and identify endometriosis.
An observational case-control study was conducted on a group (n = 149) of fertile age women. After surgery, Group A was selected upon the diagnosis of endometriosis (n = 34); Group B (n = 115) represented the controls. Demographics, comorbidities and clinical findings were registered and analysed.
Appendicitis of various grades of severity was diagnosed in all patients, but SUP was also identified in 23%, of which 14.7% also presented with endometriosis of the appendix. Women in Group A reported chronic pelvic pain, dysmenorrhoea, dyspareunia and oral contraceptive use more frequently. At multivariate analysis, factors associated with endometriosis were: age <40 years, autoimmune disorders, multiple allergies, abdominal chronic pain, associated gynaecological pain symptoms, Alvarado score ≤6, and inconclusive ultrasound findings.
The incidental finding of SUP in fertile age women presenting with an acute RIF pain and undergoing emergency surgery is a relevant observation. Clinical history and symptoms should guide surgeons in performing a correct diagnosis and in referring the patient to the gynaecology specialist.
本研究旨在评估因右髂窝(RIF)疼痛而接受急症阑尾切除术的育龄妇女中存在的浅表腹膜内异症(SUP),并考虑哪些因素可能有助于怀疑和识别内异症。
对一组(n=149)育龄妇女进行了一项观察性病例对照研究。手术后,根据内异症的诊断(n=34)选择 A 组;B 组(n=115)为对照组。记录并分析了人口统计学、合并症和临床发现。
所有患者均诊断为不同严重程度的阑尾炎,但也发现 23%的患者存在 SUP,其中 14.7%的患者还存在阑尾内异症。A 组的女性更频繁地报告慢性盆腔疼痛、痛经、性交痛和口服避孕药的使用。多因素分析显示,与内异症相关的因素为:年龄<40 岁、自身免疫性疾病、多种过敏、腹部慢性疼痛、伴发妇科疼痛症状、Alvarado 评分≤6 分、超声检查结果不确定。
在因急性 RIF 疼痛而接受急症手术的育龄妇女中偶然发现 SUP 是一个重要的观察结果。临床病史和症状应指导外科医生做出正确诊断,并将患者转介给妇科专家。