Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX, USA.
Department of Surgery, Children's Mercy Hospital, Kansas City, MO, USA.
Pediatr Transplant. 2020 Nov;24(7):e13817. doi: 10.1111/petr.13817. Epub 2020 Aug 18.
There is a lack of knowledge regarding menstrual cycles and contraception usage for adolescent transplant patients and families. Solid organ transplant patients start teratogenic medications which have pregnancy implications. We explore adolescent female solid organ transplant recipient and guardian's contraceptive knowledge and attitudes as well as menstrual patterns.
A cross-sectional descriptive research design was utilized to collect information from adolescent female transplant patients who are on mycophenolate mofetil after solid organ transplant and their guardians within our freestanding children's hospital via a survey. The sample consisted of all female adolescent patients who have completed a solid organ transplant and are on mycophenolate mofetil from April 2016 through May 2017.
Twenty-one patients were approached, of which nineteen patients and seventeen guardians completed the survey. The average age of the patient was 16.2 years. The average age at time of transplant was 12.2 years. The type of transplants includes renal (57.1%), heart (23.8%), and liver (4.8%). There were six patients (33.3%) who had a history of sexual activity; among these patients, the mean number of partners in the last year was 1.2. Menstrual concerns included dysmenorrhea, irregular bleeding, and heavy bleeding pre- and post-transplant, respectively. Participants reported contraceptive counseling prior to and after transplant approximately half of the time.
Adolescent solid organ transplant patients have multiple reproductive needs including contraception, dysmenorrhea, and irregular bleeding. Integration of contraceptive knowledge into clinical care received by adolescents with solid organ transplants is supported by knowledge gained through this study.
青少年器官移植患者及其家属对月经周期和避孕措施的了解有限。实体器官移植患者开始使用具有妊娠风险的致畸药物。我们研究了青少年女性实体器官移植受者及其监护人的避孕知识、态度和月经模式。
采用横断面描述性研究设计，在我们的独立儿童医院通过问卷调查，收集接受麦考酚酸酯的青少年女性实体器官移植患者及其监护人的信息。样本包括所有在 2016 年 4 月至 2017 年 5 月期间完成实体器官移植且正在服用麦考酚酸酯的女性青少年患者。
共接触 21 名患者，其中 19 名患者和 17 名监护人完成了调查。患者的平均年龄为 16.2 岁。移植时的平均年龄为 12.2 岁。移植类型包括肾脏（57.1%）、心脏（23.8%）和肝脏（4.8%）。有 6 名（33.3%）患者有过性行为；其中，患者在过去一年中的平均伴侣数为 1.2。月经问题包括痛经、不规则出血和移植前后大出血。参与者报告称，在移植前后接受过避孕咨询，但时间约为一半。
青少年实体器官移植患者有多种生殖需求，包括避孕、痛经和不规则出血。通过本研究获得的知识支持将避孕知识纳入青少年实体器官移植患者的临床护理中。
