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2005 年至 2014 年期间,向美国一家国家毒物控制中心报告的与伴侣动物有关的潜在有毒物质暴露情况。

Companion animal exposures to potentially poisonous substances reported to a national poison control center in the United States in 2005 through 2014.

出版信息

J Am Vet Med Assoc. 2020 Sep 1;257(5):517-530. doi: 10.2460/javma.257.5.517.

Abstract

OBJECTIVE

To evaluate data concerning suspected companion animal exposures to possibly hazardous substances reported during telephone calls to the US Animal Poison Control Center (APCC) for characterization of dog and cat exposures to potentially toxic substances in the United States.

SAMPLE

Household-level poisonings events involving dogs and cats in the United States that were reported to the APCC in 2005 through 2014.

PROCEDURES

Substances involved in reported poisonings of dogs and cats were classified into 20 general categories, and descriptive statistical analysis was used to examine the most common categories. Case fatality ratios were estimated for all exposure categories for which a final outcome status of the affected animal was documented.

RESULTS

Over the 10-year study period, 241,261 household-level poisoning events were reported to the APCC from across the United States, of which 86.0% and 14.0% involved dogs and cats, respectively. The most common agent categories reported for dogs included human medicines, foods, and pesticides. The most common agent categories reported for cats included human medicines, plants, and veterinary medicines. Chocolate and plants were the most commonly reported exposures of dogs and cats, respectively. Fluorouracil (65.2%) and bifenthrin (66.7%) were found to have the highest case fatality ratio for dogs and cats, respectively.

CONCLUSIONS AND CLINICAL RELEVANCE

The APCC call data can be used to identify the most common toxicological exposures of dogs and cats, understand the epidemiological aspects of these poisonings, and inform education programs for owners and veterinarians. Data from the APCC may be suitable for surveillance of toxicological exposures of companion animals in the United States.

摘要

目的

评估美国动物毒物控制中心(APCC)接到的疑似伴侣动物接触可能危险物质的电话报告中的数据,以描述美国犬猫接触潜在有毒物质的情况。

样本

2005 年至 2014 年向 APCC 报告的涉及美国家庭犬猫的中毒事件。

程序

将报告的犬猫中毒涉及的物质分为 20 个一般类别,采用描述性统计分析方法,检查最常见的类别。对于记录了受影响动物最终结局的所有暴露类别,估计病死率。

结果

在 10 年的研究期间,全美共有 241261 起家庭中毒事件向 APCC 报告,其中 86.0%和 14.0%分别涉及犬和猫。报告的犬最常见的药物类别包括人类药物、食品和杀虫剂。报告的猫最常见的药物类别包括人类药物、植物和兽医药物。巧克力和植物分别是犬和猫最常见的报告暴露物。氟尿嘧啶(65.2%)和二氯苯醚菊酯(66.7%)分别是犬和猫的病死率最高的药物。

结论和临床相关性

APCC 电话数据可用于识别犬猫最常见的毒理学暴露,了解这些中毒的流行病学方面,并为犬猫主人和兽医提供教育计划。APCC 的数据可能适合监测美国伴侣动物的毒理学暴露。

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