University of Massachusetts Medical School, Worcester, Massachusetts.
Meyers Primary Care Institute, Worcester, Massachusetts.
J Am Geriatr Soc. 2020 Nov;68(11):2551-2557. doi: 10.1111/jgs.16770. Epub 2020 Aug 20.
BACKGROUND/OBJECTIVES: Adverse events (AEs) occur frequently in long-term care (LTC) residents transitioning from the hospital back to an LTC facility. Measuring the association between resident characteristics and AEs can inform AE risk reduction strategies.
Prospective cohort analysis.
A total of 32 nursing homes from six New England states.
A total of 555 LTC residents contributing 762 transitions from the hospital back to LTC.
We measured the association between all AEs and preventable AEs developing in the 45 days following discharge back to LTC and demographic variables, hospital length of stay (LOS), Charlson Comorbidity Index (CCI) (0-1, 2-3, 4-5 and ≥6), dependency in activities of daily living (ADLs) using the Minimum Data Set Long Form Scale (in quintiles 0-12, 13-15, 16, 17-18, and ≥19), and number of regularly scheduled medications (0-9, 10-13, 14-17, and ≥18). To understand the independent association of each resident characteristic with AEs and preventable AEs, we constructed multiple Cox proportional hazards models.
There were 283 discharges with one or more AEs and 212 with preventable AEs. Characteristics independently associated with higher risk of an AE included hospital LOS 9 or more days (hazard ratio [HR] = 1.49; 95% confidence interval [CI] = 1.02-2.17); CCI of 4 to 5 (HR = 1.74; 95% CI = 1.13-2.67) or 6 or higher (HR = 1.58; 95% CI = 1.01-2.46); 18 or more regularly scheduled medications (HR = 1.53; 95% CI = 1.07-2.18); and 19 and above on ADL dependency (HR = 1.78; 95% CI = 1.21-2.62). Results from models with preventable AEs were similar to those with all AEs.
Increased LOS, higher comorbidity burden, greater dependency in ADLs, and polypharmacy were the resident characteristics most strongly associated with risk of AEs and preventable AEs. We recommend heightened vigilance in the care of LTC residents with these characteristics transitioning back to LTC. We also recommend research to assess strategies to reduce the risk of AEs.
背景/目的:在从医院返回长期护理(LTC)机构的过程中,长期护理居民经常发生不良事件(AE)。衡量居民特征与 AE 之间的关联可以为降低 AE 风险提供信息。
前瞻性队列分析。
来自新英格兰六个州的 32 家养老院。
共有 555 名 LTC 居民参与了总计 762 次从医院返回 LTC 的转院。
我们测量了所有 AE 和可预防 AE 在出院后 45 天内的发展与人口统计学变量、住院时间(LOS)、Charlson 合并症指数(CCI)(0-1、2-3、4-5 和≥6)、日常生活活动(ADL)的依赖程度(使用最低数据组长格式量表,分为五分位数 0-12、13-15、16、17-18 和≥19)以及定期服用的药物数量(0-9、10-13、14-17 和≥18)之间的关联。为了了解每个居民特征与 AE 和可预防 AE 的独立关联,我们构建了多个 Cox 比例风险模型。
有 283 次出院有一个或多个 AE,212 次出院有可预防的 AE。与 AE 风险增加相关的特征包括住院时间 9 天或以上(风险比[HR] = 1.49;95%置信区间[CI] = 1.02-2.17);CCI 为 4-5(HR = 1.74;95% CI = 1.13-2.67)或 6 或更高(HR = 1.58;95% CI = 1.01-2.46);定期服用 18 种或以上药物(HR = 1.53;95% CI = 1.07-2.18);ADL 依赖性为 19 或更高(HR = 1.78;95% CI = 1.21-2.62)。可预防 AE 模型和所有 AE 模型的结果相似。
住院时间延长、更高的合并症负担、ADL 依赖性增加和多药治疗是与 AE 和可预防 AE 风险最相关的居民特征。我们建议对具有这些特征的返回 LTC 的居民保持高度警惕。我们还建议进行研究,以评估降低 AE 风险的策略。