Lin C J, Xi S X, Wang J
Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai 200031, China.
Zhonghua Yi Xue Za Zhi. 2020 Aug 25;100(32):2503-2506. doi: 10.3760/cma.j.cn112137-20191202-02621.
To compare the effects of vestibular rehabilitation training and drug therapy on the symptoms of vertigo and disability in patients with vestibular peripheral vertigo. This prospective study was enrolled 43 patients with vestibular peripheral vertigo who admitted to the outpatient department of Eye & ENT Hospital of Fudan University from January 2018 to December 2018. They were randomly divided into two groups: control group (drug treatment group) and experimental group (drug treatment combined rehabilitation training group). All patients filled in the first vertigo disability rating scale (DHI), specific activity balance confidence scale (ABC) and anxiety self-rating scale (SAS) on the day of treatment and at two, four and eight weeks after treatment intervention, and the data were statistically analyzed. There was no significant difference in gender, age and body weight between the two groups (0.05). After treatment (Control group (4w) : DHI (45.5±30.6) , ABC (86.9±12.4) , SAS (37.9±8.2) Experimental group (8w) : DHI (34.8±28.5) , SAS (35.7±7.9) ) , the three scales of the two groups were better than before treatment (Control group: DHI (59.2±25.9) , ABC (79.7±16.7) ,SAS (41.1±6.8) ; Experimental group: DHI (55.2±20.5) , ABC (80.3±18.3) , SAS (41.9±9.1) ) . The comparison of data before and after treatment in each group according to treatment time indicated that DHI and ABC scores in the experimental group showed that the DHI and ABC scores of the experimental group changed significantly at 2 weeks after treatment, and the SAS scores changed at 4 weeks after treatment. The difference was statistically significant (0.05). However, there was a statistically significant difference between the control group DHI score 4 weeks after treatment and SAS score 8 weeks after treatment (0.05). ABC score did not show statistical difference (0.05). The subjective symptoms and anxiety of vertigo and disability in the two groups improved obviously after treatment. Compared with drug therapy alone, drug therapy combined with vestibular rehabilitation training can significantly improve patients' subjective symptoms of vertigo and disability, as well as their anxiety and depression, so as to improve their overall quality of life.
比较前庭康复训练和药物治疗对前庭周围性眩晕患者眩晕症状及功能障碍的影响。本前瞻性研究纳入了2018年1月至2018年12月在复旦大学附属眼耳鼻喉科医院门诊就诊的43例前庭周围性眩晕患者。将他们随机分为两组:对照组(药物治疗组)和实验组(药物治疗联合康复训练组)。所有患者在治疗当天以及治疗干预后2周、4周和8周填写首次眩晕功能障碍评定量表(DHI)、特定活动平衡信心量表(ABC)和焦虑自评量表(SAS),并对数据进行统计学分析。两组患者在性别、年龄和体重方面无显著差异(P>0.05)。治疗后(对照组(4周):DHI(45.5±30.6),ABC(86.9±12.4),SAS(37.9±8.2);实验组(8周):DHI(34.8±28.5),SAS(35.7±7.9)),两组的三个量表评分均优于治疗前(对照组:DHI(59.2±25.9),ABC(79.7±16.7),SAS(41.1±6.8);实验组:DHI(55.2±20.5),ABC(80.3±18.3),SAS(41.9±9.1))。根据治疗时间对每组治疗前后数据进行比较,结果显示实验组的DHI和ABC评分表明,治疗后2周实验组的DHI和ABC评分变化显著,治疗后4周SAS评分发生变化。差异具有统计学意义(P<0.05)。然而,对照组治疗后4周的DHI评分与治疗后8周的SAS评分之间存在统计学显著差异(P<0.05)。ABC评分未显示统计学差异(P>0.05)。两组患者眩晕及功能障碍的主观症状和焦虑在治疗后均明显改善。与单纯药物治疗相比,药物治疗联合前庭康复训练可显著改善患者眩晕及功能障碍的主观症状,以及焦虑和抑郁情绪,从而提高其整体生活质量。