Suppr超能文献

孟加拉国迈门辛一家三级护理医院慢性化脓性中耳炎(CSOM)的细菌学研究

Bacteriology of Chronic Supporative Otitis Media (CSOM) at a Tertiary Care Hospital, Mymensingh.

作者信息

Khan J A, Paul S K, Chowdhury C S, Mostafa M G, Kamruzzaman M, Paul B K, Rahman A, Sarkar S, Al-Hasan F, Alam M M, Hore A

机构信息

Dr Mohammad Jahangir Alam Khan, Associate Professor, Department of ENT, Mymensingh Medical College (MMC), Mymensingh, Bangladesh; E-mail:

出版信息

Mymensingh Med J. 2020 Jul;29(3):545-552.

Abstract

Chronic suppurative otitis media (CSOM) is a notorious infection in developing countries causing serious local damage and threatening complications. It was a cross sectional observational study to isolate and identify aerobic bacteria and to analyze the susceptibility pattern of the aerobic bacterial isolates. It was carried out from March 2017 to July 2018 in the department of Microbiology, Mymensingh Medical College, Mymensingh, Bangladesh. Samples were collected from Outpatient of ENT department, MMCH. Out of a total 300 patients with CSOM were enrolled in this study and 209 were culture positive. Among them gram negative organisms were 129(61.72%) and gram positive organisms were 70(33.49%). The most frequently isolated organism in this study was Pseudomonas aeruginosa 72(34.44%), gram positive organisms S. aureus 63(30.14%), E. coli 21(10.04%), other Pseudomonas spp (other than P. aeruginosa) 15(7.17%), mixed bacterial infectios 10(4.78%), Proteus spp 9(4.30%), CoNS 7(3.34%), Klebsiela lspp 7(3.34%), Acinetobactor spp 5(2.39%). P. aeruginosa isolates had least resistant to imipenem and colistin, S. aureus were showed high sensitivity to Vancomycin and Linezolid and E. coli were sensitive to imipenem and amikacin, ciprofloxacin and amikacin respectively. Pseudomonas aeruginosa was the most common bacteria isolated from chronic discharging ears followed by Staphylococcus aureus. Piperacillin-Tazobactum, Ciprofioxacin, Gentamicin and Amikacin were found to be the most suitable drug for Pseudomonas aeruginosa, S. aureus and E. coli. The resistance against ceftriaxone and aztreonam was found to be very high.

摘要

慢性化脓性中耳炎(CSOM)在发展中国家是一种臭名昭著的感染性疾病,会造成严重的局部损害并引发威胁生命的并发症。这是一项横断面观察性研究,旨在分离和鉴定需氧菌,并分析需氧菌分离株的药敏模式。该研究于2017年3月至2018年7月在孟加拉国迈门辛市迈门辛医学院微生物学系开展。样本取自MMCH耳鼻喉科门诊。本研究共纳入300例CSOM患者,其中209例培养阳性。其中革兰氏阴性菌有129例(61.72%),革兰氏阳性菌有70例(33.49%)。本研究中最常分离出的菌株是铜绿假单胞菌72例(34.44%),革兰氏阳性菌金黄色葡萄球菌63例(30.14%),大肠杆菌21例(10.04%),其他假单胞菌属(除铜绿假单胞菌外)15例(7.17%),混合细菌感染10例(4.78%),变形杆菌属9例(4.30%),凝固酶阴性葡萄球菌7例(3.34%),克雷伯菌属7例(3.34%),不动杆菌属5例(2.39%)。铜绿假单胞菌分离株对亚胺培南和黏菌素的耐药性最低,金黄色葡萄球菌对万古霉素和利奈唑胺表现出高敏感性,大肠杆菌分别对亚胺培南、阿米卡星、环丙沙星和阿米卡星敏感。铜绿假单胞菌是慢性流脓性耳炎中最常见分离出的细菌,其次是金黄色葡萄球菌。哌拉西林-他唑巴坦、环丙沙星、庆大霉素和阿米卡星被发现是治疗铜绿假单胞菌、金黄色葡萄球菌和大肠杆菌最适宜的药物。发现对头孢曲松和氨曲南的耐药性非常高。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验