Park Joon Soo, Page Amy T, Kruger Estie, Tennant Marc
International Research Collaborative - Oral Health and Equity, The University of Western Australia, Crawley, WA, Australia.
Pharmacy Department, Alfred Health, Melbourne, Vic., Australia.
Int Dent J. 2020 Aug 27;71(2):106-12. doi: 10.1111/idj.12605.
Dentists are independent prescribers that can prescribe subsidised medicines under the Australian Pharmaceutical Benefits Scheme (PBS). It is hypothesised that increased dental prescribing can partly be accounted for by the growth in both the Australian population and the number of practising dentists. This pharmacoepidemiological study aims to determine the dispensing patterns of medications amongst dentists and to identify trends over time.
Data on dental medications under PBS from 2006 to 2018 were accessed. All the dentist-prescribed concessional medicines dispensed at pharmacies in 2018 were included for time trend analysis. Cumulative dispensing counts and defined daily dose (DDD) per 1,000 concessional population days (DPD) were analysed for time trend analysis.
Out of the 56 medications within the dental PBS schedule, the top 20 medicines had a total cumulative dispensing count of 5,058,556, which accounts for 97.4% of the total dispensing count. Eleven out of 20 medicines were antibiotics. Overall, increases were observed for seven out of 20 medicines (amoxicillin + clavulanic acid, clindamycin, ibuprofen, diazepam, oxycodone, tramadol, naproxen) in both dispensing count and trend, as expressed per DPD.
This study highlights the increasing dispensing pattern and trends of dentist-prescribed antibiotics, opioids and benzodiazepines. Further investigation may be required to determine whether the medicine use is appropriate. In the future, this could provide new educational opportunities on the appropriate use of medicines for dentists.
牙医是独立开处方者,可根据澳大利亚药品福利计划(PBS)开具补贴药品。据推测,牙科处方量的增加部分可归因于澳大利亚人口和执业牙医数量的增长。这项药物流行病学研究旨在确定牙医开具药物的配药模式,并确定随时间的趋势。
获取了2006年至2018年PBS下牙科用药的数据。纳入了2018年在药店配药的所有牙医开具的优惠药品,进行时间趋势分析。分析了每1000个优惠人口日(DPD)的累计配药量和限定日剂量(DDD),以进行时间趋势分析。
在牙科PBS清单中的56种药物中,前20种药物的累计配药量总计为5,058,556,占总配药量的97.4%。20种药物中有11种是抗生素。总体而言,20种药物中有7种(阿莫西林+克拉维酸、克林霉素、布洛芬、地西泮、羟考酮、曲马多、萘普生)的配药量和趋势(以每DPD表示)均有所增加。
本研究突出了牙医开具的抗生素、阿片类药物和苯二氮䓬类药物的配药模式及趋势不断增加的情况。可能需要进一步调查以确定用药是否恰当。未来,这可为牙医提供关于合理用药的新教育机会。