Department of Public Health, Section of Orthopaedic Surgery, "Federico II" University, Naples, Italy.
UOSD Chirurgia della Mano e dei nervi periferici, Ospedale dei Pellegrini, Naples, Italy.
J Biol Regul Homeost Agents. 2020 May-Jun;34(3 Suppl. 2):115-120. ADVANCES IN MUSCULOSKELETAL DISEASES AND INFECTIONS - SOTIMI 2019.
The pseudoarthrosis (PSA) of scaphoid leads to alteration in load transfer in the wrist joint. Its treatment aims to achieve consolidation to improve clinical complaints and prevent post-traumatic arthritis. The indication for using vascularized bone grafts is still controversial. This prospective comparative study aimed to compare consolidation rate and time to healing of scaphoid PSA treated by volar distal radius vascularized bone graft vs non-vascularized iliac bone graft. Nine patients underwent vascularized grafting of scaphoid PSA. These patients were compared to a control group consisting of twelve patients treated with iliac crest-free bone graft. PSA consolidation was obtained in 8 of 9 patients (88%) and 9 of 12 patients (75%) in the study and control group, respectively. The difference in consolidation rate was not significant. Two of three patients with AVN of the proximal pole in the study group (66%) went to consolidation. In the control group no patient with AVN obtained bone consolidation. This difference almost reached statistical significance (p = 0.083). The mean time to consolidation was 8.6 weeks (range 8-11) and 11.7 weeks (range 10-16), respectively, in the study and control group. This difference was significant (p < 0.05). In conclusion, the distal radius vascularized graft led to satisfactory consolidation rate of PSA in the current study, even in cases of AVN of the proximal pole. Moreover, the vascularized bone graft resulted in shorter healing time compared to the non-vascularized graft.
舟状骨假关节会改变腕关节的负荷传递。其治疗目的是实现愈合,以改善临床症状并预防创伤后关节炎。使用带血管骨移植物的适应证仍存在争议。本前瞻性对照研究旨在比较掌侧桡骨远端带血管骨移植与髂骨非血管骨移植治疗舟状骨假关节的愈合率和愈合时间。9 例患者接受了舟状骨假关节的带血管移植。将这些患者与接受髂嵴游离骨移植的 12 例对照组患者进行比较。研究组和对照组分别有 8 例(88%)和 9 例(75%)患者获得 PSA 愈合。愈合率的差异无统计学意义。研究组中有 3 例近端干骺端骨坏死患者中有 2 例(66%)获得愈合。对照组中无骨坏死患者获得骨愈合。这种差异几乎具有统计学意义(p = 0.083)。研究组和对照组的平均愈合时间分别为 8.6 周(8-11 周)和 11.7 周(10-16 周)。差异有统计学意义(p < 0.05)。总之,在本研究中,桡骨远端带血管移植物导致 PSA 的愈合率令人满意,即使在近端干骺端骨坏死的情况下也是如此。此外,与非血管化移植物相比,带血管骨移植物可导致愈合时间缩短。