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胫骨后倾角大且胫骨前位移过度是初次前交叉韧带重建失败的预测性危险因素:一项前瞻性病例对照研究。

Steep Posterior Tibial Slope and Excessive Anterior Tibial Translation Are Predictive Risk Factors of Primary Anterior Cruciate Ligament Reconstruction Failure: A Case-Control Study With Prospectively Collected Data.

机构信息

Sports Medicine Service, Beijing Jishuitan Hospital, Beijing, China.

出版信息

Am J Sports Med. 2020 Oct;48(12):2954-2961. doi: 10.1177/0363546520949212. Epub 2020 Aug 31.

Abstract

BACKGROUND

Steep posterior tibial slope (PTS) and excessive anterior tibial translation (ATT) have been identified as important anatomic risk factors for anterior cruciate ligament (ACL) injury, which have raised concerns about clinical outcomes after primary ACL reconstruction (ACLR).

PURPOSE

To investigate anatomic risk factors of primary ACLR failure and to determine the cutoff values of PTS and ATT for predicting primary ACLR failure.

STUDY DESIGN

Case-control study; Level of evidence, 3.

METHODS

Between November 2015 and May 2017, a total of 215 consecutive patients with clinically diagnosed noncontact ACL injuries who underwent primary anatomic ACLR were retrospectively analyzed. Among them, 25 patients who showed complete discontinuity of ACL fibers on final follow-up magnetic resonance imaging scans were allocated into the failure group (study group). They were matched 1:2 to 50 control participants who showed clear and continuous ACL fibers on magnetic resonance imaging scans (control group). PTS and ATT were measured on preoperative weightbearing whole leg lateral radiographs and compared between the groups. The cutoff values of PTS and ATT for predicting primary ACLR failure were determined by the receiver operating characteristic curve. Moreover, predictors of primary ACLR failure were assessed by multivariate logistic regression analysis, including sex, age, body mass index, concomitant meniscal tears, degree of pivot-shift test, and KT-1000 arthrometer side-to-side difference, PTS, and ATT.

RESULTS

PTS and ATT values in the study group were significantly higher than those in the control group (mean ± SD: PTS, 17.2°± 2.2° vs 14.4°± 2.8°; ATT, 8.3 ± 3.4 mm vs 4.1 ± 3.1 mm; < .001). The cutoff values of PTS and ATT for predicting primary ACLR failure were 17° (sensitivity, 66.7%; specificity, 90.9%) and 6 mm (sensitivity, 87.5%; specificity, 79.5%), respectively. Additionally, PTS ≥17° (odds ratio, 15.6; 95% CI, 2.7-91.5; = .002) and ATT ≥6 mm (odds ratio, 9.9; 95% CI, 1.9-51.4; = .006) were determined to be risk factors of primary ACLR failure, whereas sex, age, body mass index, concomitant meniscal tears, degree of the pivot-shift test, and KT-1000 arthrometer side-to-side difference were not.

CONCLUSION

In this study, PTS ≥17° and ATT ≥6 mm, as measured on weightbearing whole leg radiographs, were identified to be predictive risk factors of primary ACLR failure. This study adds to the existing knowledge about potential surgical indications of simultaneous slope-reducing high tibial osteotomy to mitigate the primary ACLR failure rate.

摘要

背景

陡峭的胫骨后倾角(PTS)和过大的胫骨前向位移(ATT)已被确定为前交叉韧带(ACL)损伤的重要解剖学危险因素,这引起了人们对初次 ACL 重建(ACLR)后临床结果的担忧。

目的

探讨初次 ACLR 失败的解剖学危险因素,并确定 PTS 和 ATT 的截断值,以预测初次 ACLR 失败。

研究设计

病例对照研究;证据等级,3 级。

方法

回顾性分析了 2015 年 11 月至 2017 年 5 月期间 215 例临床诊断为非接触性 ACL 损伤且接受初次解剖 ACLR 的连续患者。其中,25 例最终随访磁共振成像扫描显示 ACL 纤维完全中断的患者被分配到失败组(研究组)。他们按照 1:2 的比例与 50 名磁共振成像扫描显示 ACL 纤维清晰连续的对照组参与者相匹配(对照组)。在术前负重全腿侧位 X 线片上测量 PTS 和 ATT,并对两组进行比较。通过受试者工作特征曲线确定 PTS 和 ATT 预测初次 ACLR 失败的截断值。此外,通过多变量逻辑回归分析评估初次 ACLR 失败的预测因素,包括性别、年龄、体重指数、合并半月板撕裂、髌股关节试验的移位程度以及 KT-1000 关节测径仪的侧间差值、PTS 和 ATT。

结果

研究组 PTS 和 ATT 值明显高于对照组(均值±标准差:PTS,17.2°±2.2°比 14.4°±2.8°;ATT,8.3±3.4mm 比 4.1±3.1mm;均<0.001)。PTS 和 ATT 预测初次 ACLR 失败的截断值分别为 17°(敏感性,66.7%;特异性,90.9%)和 6mm(敏感性,87.5%;特异性,79.5%)。此外,PTS≥17°(比值比,15.6;95%置信区间,2.7-91.5;=0.002)和 ATT≥6mm(比值比,9.9;95%置信区间,1.9-51.4;=0.006)被确定为初次 ACLR 失败的危险因素,而性别、年龄、体重指数、合并半月板撕裂、髌股关节试验的移位程度以及 KT-1000 关节测径仪的侧间差值则不是。

结论

在这项研究中,负重全腿 X 线片上测量的 PTS≥17°和 ATT≥6mm 被确定为初次 ACLR 失败的预测危险因素。本研究增加了关于同时进行胫骨高位截骨术以降低初次 ACLR 失败率的潜在手术适应证的知识。

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