Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA.
VA Connecticut Health System, West Haven, Connecticut, USA.
J Dual Diagn. 2020 Oct;16(4):373-381. doi: 10.1080/15504263.2020.1808749. Epub 2020 Aug 31.
The aim of this study was to examine health, demographic, and service utilization characteristics of veterans with multimorbid tobacco use disorder (TUD) and morbid obesity compared to those with either condition alone. Health record data were extracted from the computerized patient record system of the Veterans Health Administration (VHA; October 1, 2011 to September 30, 2012). Bivariate and multivariate logistic regression models were used to compare veterans with both TUD and morbid obesity (body mass index [BMI] ≥ 40 kg/m) to veterans with each condition alone on a range of demographic, health, and service utilization outcome variables that also were extracted from the VHA administrative record. Veterans with both morbid obesity and TUD showed higher rates of medical and psychiatric comorbidity than did veterans with either condition alone. However, while veterans with TUD and morbid obesity showed higher rates of comorbid substance use disorders than veterans with morbid obesity alone, veterans with both conditions showed substantially lower rates of substance use disorders than those with TUD alone. Veterans with co-occurring morbid obesity and TUD appear to be at greater risk for medical disease and psychiatric conditions. The unexpected finding that veterans with TUD alone had more concurrent substance use disorders than veterans with both TUD and morbid obesity suggest the possibility that overeating may be a substitute for substance use in the context of TUD. The multimorbidity profile described here may suggest unique treatment needs for individuals with both TUD and morbid obesity. Highlights Medical multimorbidities predict additional health conditions and poorer outcomes. Obesity and tobacco use may share common underlying vulnerabilities. Veterans with both conditions showed higher rates of certain multimorbidities. Obesity may protect against substance use in tobacco users.
这项研究的目的是检查患有多种烟草使用障碍(TUD)和病态肥胖的退伍军人与仅患有其中一种疾病的退伍军人在健康、人口统计学和服务利用方面的特征。健康记录数据从退伍军人事务部(VHA)的计算机患者记录系统中提取(2011 年 10 月 1 日至 2012 年 9 月 30 日)。使用二变量和多变量逻辑回归模型,比较同时患有 TUD 和病态肥胖(体重指数[BMI]≥40kg/m)的退伍军人与仅患有其中一种疾病的退伍军人在一系列人口统计学、健康和服务利用结果变量上的差异,这些变量也从 VHA 行政记录中提取。同时患有病态肥胖和 TUD 的退伍军人比仅患有其中一种疾病的退伍军人有更高的医疗和精神共病率。然而,尽管同时患有 TUD 和病态肥胖的退伍军人比仅患有病态肥胖的退伍军人有更高的共患物质使用障碍率,但同时患有这两种疾病的退伍军人比仅患有 TUD 的退伍军人物质使用障碍率要低得多。同时患有病态肥胖和 TUD 的退伍军人似乎面临更大的医疗疾病和精神疾病风险。令人意外的是,仅患有 TUD 的退伍军人比同时患有 TUD 和病态肥胖的退伍军人有更多的同时存在的物质使用障碍,这表明在 TUD 的情况下,暴饮暴食可能是物质使用的替代物。这里描述的多重病态特征可能表明同时患有 TUD 和病态肥胖的个体存在独特的治疗需求。要点医疗多重病态可预测其他健康状况和较差的结局。肥胖和烟草使用可能有共同的潜在弱点。同时患有这两种疾病的退伍军人有更高的某些多重病态率。肥胖可能在烟草使用者中预防物质使用。