Department of Internal Medicine III (Cardiology, Angiology, and Intensive Care) of the Saarland University Medical Center, Saarland University; Kirrberger Str. 100, Building 24; 66421 Homburg/Saar, Germany.
Department of Internal Medicine III (Cardiology, Angiology, and Intensive Care) of the Saarland University Medical Center, Saarland University; Kirrberger Str. 100, Building 24; 66421 Homburg/Saar, Germany.
J Affect Disord. 2020 Nov 1;276:380-387. doi: 10.1016/j.jad.2020.06.065. Epub 2020 Jul 15.
It has been shown that heart-focused anxiety raises the risk of adverse outcomes in patients with heart disease. Yet, there is a lack of studies investigating this association. We aim at identifying predictors of heart-focused anxiety in patients with stable heart failure to facilitate the identification of individuals with increased risk for adverse outcomes.
We assessed heart-focused anxiety and a set of psychological, demographic/lifestyle, and medical/laboratory variables in a sample of 107 patients with stable chronic heart failure to identify predictors of heart-focused anxiety.
Heart-focused anxiety was best predicted by self-reported anxiety and quality of life. Moreover, the personality dimension conscientiousness as well as physical activity, and the laboratory value of renal function, the estimated glomerular filtration rate (eGFR), had predictive validity for heart-focused anxiety.
The present findings should be replicated in a longitudinal design with a less selective sample including more women and participants with more divers ethnical backgrounds.
Heart-focused anxiety is predictable by psychological and lifestyle variables. eGFR, as a laboratory marker for renal function, showed also predictive validity. The awareness of such predictors may help detecting comorbid underlying heart-focused anxiety and thus identify patients with an increased need for psychological care.
已有研究表明,心脏相关焦虑会增加心脏病患者不良结局的风险。然而,目前缺乏相关研究。我们旨在确定稳定心力衰竭患者中心脏相关焦虑的预测因素,以便于识别具有不良结局高风险的个体。
我们评估了 107 例稳定慢性心力衰竭患者的心脏相关焦虑和一系列心理、人口统计学/生活方式以及医学/实验室变量,以确定心脏相关焦虑的预测因素。
自我报告的焦虑和生活质量对心脏相关焦虑的预测效果最佳。此外,人格维度中的尽责性以及身体活动和肾功能的实验室值(肾小球滤过率估计值,eGFR)对心脏相关焦虑也具有预测效力。
本研究结果应在具有更少选择性的样本中,采用纵向设计进行复制,包括更多女性和具有更多不同种族背景的参与者。
心理和生活方式变量可预测心脏相关焦虑。作为肾功能的实验室标志物,eGFR 也具有预测效力。了解这些预测因素有助于发现潜在的共患心脏相关焦虑,并确定需要更多心理关怀的患者。