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序贯苍白球内侧部切开术治疗腹部肌张力障碍 2 年随访结果

Successful Relief of Abdominal Dystonia After Sequential GPi Pallidotomy with 2-Year Follow-Up.

机构信息

Post Graduate Doctoral Program, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Department of Neurosurgery, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.

Department of Neurosurgery, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.

出版信息

World Neurosurg. 2020 Dec;144:68-70. doi: 10.1016/j.wneu.2020.08.152. Epub 2020 Sep 1.

Abstract

BACKGROUND

Abdominal dystonia is very rare. To our knowledge, no clinical study has reported its specific treatment. Stereotactic therapy has been used to treat several movement disorders, including focal and general dystonia. We investigated the use of internal globus pallidum (GPi) pallidotomy for abdominal dystonia after failed oral medication.

CASE DESCRIPTION

A 48-year-old man presented with abdominal dystonia and complaints of involuntary undulating and contraction movements of his left abdominal wall for 5 years. Treatment with oral medication for 4 years was ineffective. Lesioning of the right GPi successfully relieved his symptoms. The symptoms recurred at 3 months and right GPi pallidotomy was repeated with complete resolution of symptoms after the second procedure. There was no recurrence or focal deficit at the 2-year follow-up.

CONCLUSIONS

GPi pallidotomy is feasible and effective for the treatment of abdominal dystonia that is resistant to standard medical therapy.

摘要

背景

腹部肌张力障碍非常罕见。据我们所知,尚无临床研究报道其具体的治疗方法。立体定向治疗已被用于治疗多种运动障碍,包括局灶性和全身性肌张力障碍。我们研究了在口服药物治疗失败后,使用内侧苍白球(GPi)苍白球切开术治疗腹部肌张力障碍。

病例描述

一名 48 岁男性,因腹部肌张力障碍和左腹壁不自主波动和收缩运动 5 年来就诊。4 年的口服药物治疗无效。右侧 GPi 损毁术成功缓解了他的症状。术后 3 个月症状再次出现,再次进行右侧 GPi 苍白球切开术,第二次手术后症状完全缓解。在 2 年的随访中无复发或局灶性缺陷。

结论

GPi 苍白球切开术对于标准药物治疗抵抗的腹部肌张力障碍是可行且有效的治疗方法。

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