Cole N A, Purdy C W, Hallford D M
U.S. Department of Agriculture, Bushland, TX 79012.
J Anim Sci. 1988 Mar;66(3):798-805. doi: 10.2527/jas1988.663798x.
Trials were conducted to determine the influence of feed and water deprivation on feed intake, plasma glucose, free fatty acids (FFA), urea-N (PUN), serum insulin and growth hormone (GH) in lambs. In Trial 1, 12 Hampshire X Suffolk lambs (avg wt 30.5 kg) were deprived of feed and water for 0, 24, 48 or 72 h. During the first 8 d of realimentation, feed intake was depressed more (P less than .05) by longer periods of deprivation. In Trial 2, 12 crossbred lambs (avg wt 50 kg) were deprived of feed and water for 0 or 72 h. During the first 4 d of realimentation, feed intake was lower (P less than .05) in deprived than in fed lambs. The depressed feed intake could be detected within 30 min of feeding. In Trial 3, 12 crossbred lambs (avg wt 40 kg) were fasted for 0 or 72 h, and blood samples were obtained at -5, 30, 60, 120 and 180 min postprandial. On the 1st d of realimentation, lambs previously fasted had abnormal serum hormone patterns compared with nonfasted controls. On d 2 of realimentation, lambs previously fasted had higher (P less than .05) insulin, glucose and FFA than controls. On d 4 of realimentation, lambs previously fasted had higher insulin:GH ratios and lower PUN than controls. Results of these trials suggest that depriving lambs of feed and water for 72 h reduces subsequent feed intake for 4 d or more. Postprandial blood metabolite patterns are abnormal for a similar length of time.
进行了多项试验，以确定禁食和禁水对羔羊采食量、血浆葡萄糖、游离脂肪酸（FFA）、尿素氮（PUN）、血清胰岛素和生长激素（GH）的影响。在试验1中，12只汉普夏×萨福克羔羊（平均体重30.5千克）禁食和禁水0、24、48或72小时。在重新喂食的前8天，禁食时间越长，采食量下降越明显（P＜0.05）。在试验2中，12只杂种羔羊（平均体重50千克）禁食和禁水0或72小时。在重新喂食的前4天，禁食羔羊的采食量低于喂食羔羊（P＜0.05）。在喂食后30分钟内即可检测到采食量下降。在试验3中，12只杂种羔羊（平均体重40千克）禁食0或72小时，并在餐后-5、30、60、120和180分钟采集血样。在重新喂食的第1天，与未禁食的对照组相比，先前禁食的羔羊血清激素模式异常。在重新喂食的第2天，先前禁食的羔羊的胰岛素、葡萄糖和FFA水平高于对照组（P＜0.05）。在重新喂食的第4天，先前禁食的羔羊的胰岛素:GH比值较高，PUN水平低于对照组。这些试验结果表明，羔羊禁食和禁水72小时会使随后4天或更长时间的采食量减少。餐后血液代谢物模式在类似的时间段内也会异常。
