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一例 4 岁儿童由副黏液病毒引起的横纹肌溶解和多器官功能障碍的罕见病例。

A rare case of metapneumovirus-induced rhabdomyolysis and multi-organ dysfunction in a 4-year-old child.

机构信息

Department of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

出版信息

Paediatr Int Child Health. 2021 May;41(2):166-169. doi: 10.1080/20469047.2020.1814567. Epub 2020 Sep 10.

Abstract

Human metapneumovirus (hMPV) is a common cause of acute respiratory tract infections in children. In immunocompetent individuals, the course of hMPV infection is usually benign and self-limiting. A developmentally normal, previously healthy 4-year-old girl presented with pneumonia and later developed rhabdomyolysis and multi-organ dysfunction syndrome (MODS) which was fatal. Extensive microbiological investigation for a possible viral aetiology was positive only for hMPV, thus making it the first reported case of hMPV infection-related rhabdomyolysis.: ARDS, acute respiratory distress syndrome; CK, creatinine kinase; hMPV, human metapneumovirus; MODS, multi-organ dysfunction syndrome; RSV, respiratory syncytial virus.

摘要

人偏肺病毒(hMPV)是儿童急性呼吸道感染的常见病因。在免疫功能正常的个体中,hMPV 感染的病程通常是良性的和自限性的。一名发育正常、既往健康的 4 岁女孩因肺炎就诊,随后发展为横纹肌溶解症和多器官功能障碍综合征(MODS),最终导致死亡。为明确可能的病毒病因进行了广泛的微生物学调查,仅 hMPV 呈阳性,这使其成为首例报道的与 hMPV 感染相关的横纹肌溶解症病例。:ARDS,急性呼吸窘迫综合征;CK,肌酸激酶;hMPV,人偏肺病毒;MODS,多器官功能障碍综合征;RSV,呼吸道合胞病毒。

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