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溃疡性结肠炎和克罗恩病炎症性肠病问卷土耳其语版的验证和可靠性。

Validation and reliability of the Turkish version of the inflammatory bowel disease questionnaire for ulcerative colitis and Crohn's disease.

机构信息

Department of Gastroenterology, Marmara University School of Medicine, İstanbul, Turkey.

Department of Internal Medicine, Marmara University School of Medicine, İstanbul, Turkey.

出版信息

Turk J Gastroenterol. 2020 Aug;31(8):566-572. doi: 10.5152/tjg.2020.19553.

Abstract

BACKGROUND/AIMS: Inflammatory bowel diseases (IBD) impairs patients' quality of life (QoL). Inflammatory bowel disease questionnaire (IBDQ) is created to measure the health-related QoL specific for IBD. We planned to investigate the validation and reliability of the Turkish translation of IBDQ.

MATERIALS AND METHODS

Patients filled self-report questionnaires (Turkish Inflammatory bowel disease questionnaire (TrIBDQ) and Short Form-36 (SF-36)) themselves under a physician's supervision, and they were free to ask questions about the questionnaires. The participants then filled the same questionnaire after at least two weeks. Construct validity, discriminant ability, reliability, and susceptibility to change were analyzed separately for the IBD patients. Intra-class correlation coefficient (ICC) was used to assess test-retest reliability. Cronbach's alpha values were used to assess internal consistency.

RESULTS

A hundred patients enrolled in the study, 53 with Crohn's disease (CD), 47 with ulcerative colitis (UC). We found a moderate to high positive correlation between the TrIBDQ domains and the SF-36 dimensions. In UC and CD, TrIBDQ was able to differentiate active disease and remission. We found Cronbach's alpha for TrIBDQ domains ranged from 0.76-0.94 in CD and from 0.79-0.92 in UC. The total Cronbach's alpha for TrIBDQ was 0.96 in CD and 0.95 in UC. Sensitivity-to-change analyses of the bowel, systemic, and emotional scores showed statistically significant differences between their baseline and follow-up values.

CONCLUSION

TrIBDQ is a valid and reliable tool for assessing the quality of life in Turkish speaking IBD patients. Thus it can be used in clinical research and practice.

摘要

背景/目的:炎症性肠病(IBD)会降低患者的生活质量(QoL)。炎症性肠病问卷(IBDQ)是为衡量与 IBD 相关的特定健康相关生活质量而创建的。我们计划研究土耳其语翻译的 IBDQ 的验证和可靠性。

材料和方法

在医生的监督下,患者自行填写自我报告问卷(土耳其炎症性肠病问卷(TrIBDQ)和简短形式 36 项健康调查(SF-36)),并可以就问卷提出问题。然后,患者在至少两周后再次填写相同的问卷。分别分析 IBD 患者的结构有效性、鉴别能力、可靠性和对变化的敏感性。采用组内相关系数(ICC)评估测试-重测可靠性。Cronbach 的 alpha 值用于评估内部一致性。

结果

本研究共纳入 100 例患者,其中 53 例为克罗恩病(CD),47 例为溃疡性结肠炎(UC)。我们发现 TrIBDQ 各领域与 SF-36 维度之间存在中度至高度正相关。在 UC 和 CD 中,TrIBDQ 能够区分活动期疾病和缓解期。我们发现 TrIBDQ 各领域的 Cronbach's alpha 值在 CD 中为 0.76-0.94,在 UC 中为 0.79-0.92。CD 中 TrIBDQ 的总 Cronbach's alpha 值为 0.96,UC 中为 0.95。肠、全身和情绪评分的敏感性变化分析显示,其基线值和随访值之间存在统计学显著差异。

结论

TrIBDQ 是一种评估土耳其语 IBD 患者生活质量的有效且可靠的工具。因此,它可以在临床研究和实践中使用。

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