Roux H, Mercier P, Jeandel P, Brouillet-Gabriel M, Serratrice G
Rev Rhum Mal Osteoartic. 1977 May;44(5):331-4.
In 89 cases of rheumatoid polyarthritis the number of B lymphocytes was shown by an immunofluorescence technique and the number T lymphocytes by a rosette test. 30 untreated polyarthritics were distinguished into two groups: in one there was no change in the number of T cellules; in the other there was a reduction in the number of T cells and lymphopenia. The same differences were found under corticotherapy (10 cases), antimalarial drugs (8 cases), penicillamine (21 cases), chrysotherapy (11 cases) and levamisole (9 cases). Levamisole only infrequently increases the number of T cellules (2/9). No relation with any developmental parameter was found in any group.
在89例类风湿性多关节炎患者中,采用免疫荧光技术检测B淋巴细胞数量,采用玫瑰花结试验检测T淋巴细胞数量。30例未经治疗的多关节炎患者被分为两组:一组T细胞数量无变化;另一组T细胞数量减少且淋巴细胞减少。在皮质激素治疗(10例)、抗疟药治疗(8例)、青霉胺治疗(21例)、金制剂治疗(11例)和左旋咪唑治疗(9例)的患者中也发现了同样的差异。左旋咪唑很少能增加T细胞数量(2/9)。在任何一组中均未发现与任何发育参数有关联。