Dep. of Pediatric Neurology, Habu Stavanger, Stavanger University Hospital, Stavanger HF, Pb 8100, 4068, Stavanger, Norway.
Dep of Clinical Medicine, Pb 7804, 5020, Bergen, Norway.
Disabil Health J. 2021 Jan;14(1):100992. doi: 10.1016/j.dhjo.2020.100992. Epub 2020 Sep 11.
Risk of psychiatric disorders has been reported for children and adolescents with cerebral palsy (CP) at different ages, however little is known regarding the long-term trajectories of these disorders.
The aim of this study was to assess the trajectories of psychiatric disorders in children with CP, and to explore their association to risk factors.
We assessed a cohort of children with CP at age seven and again at age eleven with a child psychiatric diagnostic instrument, and parents were informants. We assessed type of CP, Gross Motor Function Classification System (GMFCS) levels, and co-occurring medical conditions in a medical examination, through the medical records, and in an interview with the parents at the onset of the study.
We found a significant increase in the prevalence of emotional disorders from seven to eleven years of age (p 0.01), whereas the prevalence of behavioral disorders was stable. Half of the cohort met criteria for a psychiatric disorder at both assessment points. Type of CP, spastic bilateral or unilateral, dyskinetic or ataxic, and co-occurring medical conditions were non-significant predictors of psychiatric disorders. Subthreshold psychiatric disorders at age seven were predictive of psychiatric disorders at age eleven.
We found a persistently elevated prevalence of psychiatric disorders in children with CP. Prevalence of behavioral disorders was stable, whereas we found a significant four-fold increase in emotional disorders. Sub-threshold psychiatric disorders predicted later psychiatric disorders. Increased focus on early mental health symptoms as well as more knowledge regarding emotional disorders in children with CP seems warranted.
脑瘫(CP)患儿在不同年龄段的精神障碍风险已被报道,但对于这些障碍的长期轨迹知之甚少。
本研究旨在评估脑瘫儿童的精神障碍轨迹,并探讨其与危险因素的关系。
我们在 7 岁和 11 岁时使用儿童精神病学诊断工具评估了脑瘫儿童队列,并让父母作为信息提供者。我们通过医疗记录评估了 CP 类型、粗大运动功能分类系统(GMFCS)水平和共患的医疗状况,并在研究开始时通过与父母的访谈进行评估。
我们发现,从 7 岁到 11 岁,情绪障碍的患病率显著增加(p<0.01),而行为障碍的患病率保持稳定。一半的队列在两个评估点都符合精神障碍标准。CP 类型、痉挛性双侧或单侧、运动障碍性或共济失调性和共患的医疗状况不是精神障碍的显著预测因素。7 岁时的亚临床精神障碍是 11 岁时出现精神障碍的预测因素。
我们发现脑瘫儿童的精神障碍患病率持续升高。行为障碍的患病率保持稳定,而情绪障碍的患病率显著增加了四倍。亚临床精神障碍预测了后期的精神障碍。对脑瘫儿童早期心理健康症状的关注增加,以及对其情绪障碍的更多了解似乎是必要的。