Golestan University of Medical Science, Gorgan, Iran.
Iran J Kidney Dis. 2020 Sep;14(5):358-364.
The Resistance Index by doppler ultrasound has been characterized as a non-invasive diagnostic method that has been well predictive of the outcome of renal function in type 2 diabetic patients. This study aims to investigate the relationship between renal artery resistance index (RI) and albuminuria in diabetic patients.
This descriptive, analytical, cross-sectional study was conducted on diabetic patients referred to the clinic for ultrasonography. Patients were divided into two groups: macro albuminuria and microalbuminuria or normoalbuminuria and for all patients, ultrasonography was done using the same ultrasound machine and by the same operator. Doppler sonography of the renal arteries was performed and the results were recorded.
52.4% of the patients were female. The mean age of these patients was 50.25 ± 16.41. The mean RI in the study population was 66.0 ± 0.01. In this study, RI with albuminuria and HbA1c levels in diabetic patients were not significant. However, there was a significant relationship between RI and serum creatinine in diabetic patients, with increasing creatinine level, RI was also increased. Also, there was a significant relationship between RI and gender and this indicator had a direct relation with male gender but there was no correlation with female gender.
In the current study, the patient's albuminuria, type of treatment and HbA1c had no effect on the RI. The study also found that an increase in the RI index could be a significant predictor of renal dysfunction and increased creatinine.
多普勒超声的阻力指数已被描述为一种非侵入性诊断方法,可很好地预测 2 型糖尿病患者肾功能的结果。本研究旨在探讨糖尿病患者肾动脉阻力指数(RI)与蛋白尿之间的关系。
这是一项描述性、分析性、横断面研究,对因超声检查而就诊的糖尿病患者进行了研究。患者分为两组:大量白蛋白尿和微量白蛋白尿或正常白蛋白尿,对于所有患者,均使用同一台超声机和同一位操作员进行超声检查。对肾动脉进行多普勒超声检查并记录结果。
52.4%的患者为女性。这些患者的平均年龄为 50.25 ± 16.41 岁。研究人群的平均 RI 为 66.0 ± 0.01。在这项研究中,RI 与糖尿病患者的蛋白尿和 HbA1c 水平无显著相关性。然而,RI 与糖尿病患者的血清肌酐之间存在显著关系,随着肌酐水平的升高,RI 也升高。此外,RI 与性别之间也存在显著关系,该指标与男性直接相关,但与女性无关。
在目前的研究中,患者的蛋白尿、治疗类型和 HbA1c 对 RI 没有影响。该研究还发现,RI 指数的增加可能是肾功能障碍和肌酐升高的一个重要预测指标。