Soliman Moetaza
Department of Pharmacy Practice, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
Clin Cosmet Investig Dermatol. 2020 Aug 25;13:601-609. doi: 10.2147/CCID.S269909. eCollection 2020.
Patient-reported measures are of importance in chronic dermatological conditions where psychosocial consequences and quality of life impairment are common. The current study aimed to evaluate patient-reported disease severity and quality of life in Arabic patients with psoriasis.
Arabic psoriatic patients were invited to complete an online survey that collected patients' demographics, self-assessed Simplified Psoriasis Index (saSPI) and the Dermatology Life Quality Index (DLQI). Disease severity and quality of life were compared in relation to patients' demographics. Correlation between patient-reported measures was calculated using Spearman's rank correlation test.
A total of 221 patients with psoriasis, from 12 Arabic-speaking countries, participated in the study. The mean (95% CIs) saSPI-severity score was 10.9 (9.6-12.2). Female patients reported higher saSPI-psychosocial impact scores compared to males (P=0.04) while patients with longer disease duration reported higher saSPI-past history and interventions scores (P=0.0001). The mean (95% CIs) DLQI score was 11.2 (10.2-12.1). Patients with severe disease reported significantly higher DLQI scores [18.5 (10.5-2)] (P=0.0001). DLQI was strongly correlated with saSPI-psychosocial impact score (rho= 0.63).
Arabic psoriatic patients participating in this study showed mild to moderate disease severity which had a very large impact on patients' quality of life. Higher disease severity was associated with more impaired quality of life.
在慢性皮肤病中,患者报告的指标很重要,因为心理社会后果和生活质量受损很常见。本研究旨在评估阿拉伯语银屑病患者报告的疾病严重程度和生活质量。
邀请阿拉伯语银屑病患者完成一项在线调查,该调查收集患者的人口统计学信息、自我评估的简化银屑病指数(saSPI)和皮肤病生活质量指数(DLQI)。比较疾病严重程度和生活质量与患者人口统计学信息的关系。使用Spearman等级相关检验计算患者报告指标之间的相关性。
共有来自12个阿拉伯语国家的221名银屑病患者参与了该研究。saSPI严重程度评分的平均值(95%置信区间)为10.9(9.6 - 12.2)。女性患者报告的saSPI心理社会影响评分高于男性(P = 0.04),而病程较长的患者报告的saSPI既往史和干预评分较高(P = 0.0001)。DLQI评分的平均值(95%置信区间)为11.2(10.2 - 12.1)。重症患者报告的DLQI评分显著更高[18.5(10.5 - 2)](P = 0.0001)。DLQI与saSPI心理社会影响评分高度相关(rho = 0.63)。
参与本研究的阿拉伯语银屑病患者显示出轻度至中度的疾病严重程度,这对患者的生活质量有很大影响。更高的疾病严重程度与更受损的生活质量相关。