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治疗还是等待?中尿道吊带置入时膀胱过度活动症症状的自然围手术期过程。

Treat or Wait? Natural Perioperative Course of Overactive Bladder Symptoms at the Time of Midurethral Sling Placement.

机构信息

From the Female Pelvic Medicine and Reconstructive Surgery, University of California, Irvine School of Medicine, Irvine, CA.

Female Pelvic Medicine and Reconstructive Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL.

出版信息

Female Pelvic Med Reconstr Surg. 2021 Feb 1;27(2):e348-e351. doi: 10.1097/SPV.0000000000000927.

Abstract

OBJECTIVE

The aims of this study were to describe the perioperative course of untreated overactive bladder (OAB) (urinary frequency [UF] and urgency urinary incontinence [UUI]) before and after isolated retropubic midurethral sling (MUS) and to identify the time point for spontaneous OAB symptom improvement in the most patients.

METHODS

This is a prospective cohort study of women undergoing an isolated MUS. Women completed the Urogenital Distress Inventory 6 and Incontinence Impact Questionnaire 7 preoperatively and weekly for 13 weeks postoperatively. Bothersome UF and UUI were defined as a response of "moderately" or "greatly" bothered on questions 1 and 2 of the Urogenital Distress Inventory. The treatment for OAB was deferred until 13 weeks after surgery.

RESULTS

Fifty-four women were included with a mean ± SD age of 48 ± 9 years. Preoperatively, 41% of women reported both bothersome UF and UUI. Six weeks after surgery, only 15% and 6% reported bothersome UF and UUI (P < 0.001 and P < 0.001, respectively). Between 6 and 13 weeks, percentages of bothersome symptoms remained low (11.7% UF and 5.8% UUI). In addition, the impact of these urinary symptoms on activities, relationships, and feelings became consistently negligible (Incontinence Impact Questionnaire 7 median score <1) at 5 weeks postoperatively. Only 3 women desired treatment for UUI after the study period.

CONCLUSIONS

Overactive bladder is common before and immediately after MUS. However, the majority of patients have spontaneous symptom resolution by 6 weeks after surgery; it may be reasonable to discontinue preoperatively initiated overactive bladder treatment or defer starting treatment until this time point.

摘要

目的

本研究旨在描述未经治疗的膀胱过度活动症(OAB)(尿频率[UF]和急迫性尿失禁[UUI])在孤立耻骨后尿道中段吊带(MUS)前后的围手术期过程,并确定大多数患者自发改善 OAB 症状的时间点。

方法

这是一项对接受孤立性 MUS 的女性进行的前瞻性队列研究。女性在术前和术后 13 周内每周完成尿生殖窘迫问卷 6 和失禁影响问卷 7。UF 和 UUI 困扰被定义为尿生殖窘迫问卷第 1 和第 2 题中“中度”或“严重”困扰的回答。OAB 的治疗被推迟到手术后 13 周。

结果

54 名女性入组,平均年龄±标准差为 48±9 岁。术前,41%的女性报告 UF 和 UUI 均困扰。术后 6 周,仅 15%和 6%报告 UF 和 UUI 困扰(P<0.001 和 P<0.001)。在 6 至 13 周之间,困扰症状的百分比仍然较低(UF 为 11.7%,UUI 为 5.8%)。此外,这些尿症状对活动、人际关系和感觉的影响在术后 5 周时变得一致微不足道(失禁影响问卷 7 中位数评分<1)。只有 3 名女性在研究期间后需要治疗 UUI。

结论

OAB 在 MUS 前后很常见。然而,大多数患者在手术后 6 周内有自发症状缓解;术前开始的 OAB 治疗可能合理地停止或推迟到这个时间点开始治疗。

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