Suppr超能文献

人口统计学因素对双膦酸盐相关非典型股骨骨折发生部位的影响。

The Influence of Demographic Factors on the Location of Bisphosphonate-related Atypical Femoral Fractures.

作者信息

Yuan Wei, Kwek Ernest B K

机构信息

Department of Orthopaedic Surgery, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, 308433 Singapore.

出版信息

Indian J Orthop. 2020 Jul 28;54(Suppl 1):116-120. doi: 10.1007/s43465-020-00216-1. eCollection 2020 Sep.

Abstract

BACKGROUND

The location of bisphosphonate-related atypical femoral fractures (AFFs) is related to the femoral bow. Other factors that might also be related to the distribution of AFFs are not well studied. In this study, we attempt to define the demographic factors that influence the distribution AFFs in our local population.

MATERIALS AND METHODS

The medical records of all the patients diagnosed with AFFs treated in our institution between 2008 and 2017 were retrospectively reviewed and divided based on fracture location into subtrochanteric and mid-shaft groups. Demographic data were collected and compared between the two groups. Independent factors affecting the location of AFFs were identified via multivariate analysis.

RESULTS

Seventy-nine AFFs in 71 patients were included. Thirty-two fractures occurred at the subtrochanteric region and 47 occurred at the mid-shaft. Age, bone density, anterior femoral bow and lateral femoral bow were significantly different between the two groups, whereas height, weight, body mass index, presence of prodromal symptoms, type and duration of bisphosphonates were not significantly different. Multivariate analysis showed anterior femoral bow was the only independent factor associated with the location of AFFs.

CONCLUSIONS

Anterior femoral bow is the only factor that can predict the location of AFFs. In our population, other demographic factors were not found to be predictive.

摘要

背景

双膦酸盐相关非典型股骨骨折(AFFs)的位置与股骨弓有关。其他可能与AFFs分布相关的因素尚未得到充分研究。在本研究中,我们试图确定影响我们当地人群中AFFs分布的人口统计学因素。

材料与方法

回顾性分析2008年至2017年在我院接受治疗的所有诊断为AFFs患者的病历,并根据骨折部位分为转子下组和股骨干中段组。收集两组的人口统计学数据并进行比较。通过多变量分析确定影响AFFs部位的独立因素。

结果

纳入71例患者的79例AFFs。32例骨折发生在转子下区域,47例发生在股骨干中段。两组之间的年龄、骨密度、股骨前弓和股骨外侧弓有显著差异,而身高、体重、体重指数、前驱症状的存在、双膦酸盐的类型和使用时间无显著差异。多变量分析显示股骨前弓是与AFFs部位相关的唯一独立因素。

结论

股骨前弓是唯一能预测AFFs部位的因素。在我们的人群中,未发现其他人口统计学因素具有预测性。

相似文献

1
The Influence of Demographic Factors on the Location of Bisphosphonate-related Atypical Femoral Fractures.
Indian J Orthop. 2020 Jul 28;54(Suppl 1):116-120. doi: 10.1007/s43465-020-00216-1. eCollection 2020 Sep.
4
Mid-term outcomes after the surgical treatment of atypical femoral fractures : minimum three-year follow-up.
Bone Joint J. 2021 Nov;103-B(11):1648-1655. doi: 10.1302/0301-620X.103B11.BJJ-2021-0416.R1.
5
Factors affecting fracture location in atypical femoral fractures: A cross-sectional study with 147 patients.
Injury. 2017 Jul;48(7):1570-1574. doi: 10.1016/j.injury.2017.05.033. Epub 2017 May 25.
6
Incidence, risk factors, and fracture healing of atypical femoral fractures: a multicenter case-control study.
Osteoporos Int. 2018 Nov;29(11):2427-2435. doi: 10.1007/s00198-018-4640-4. Epub 2018 Jul 23.
7
Atypical fractures of the femur: effect of anterolateral bowing of the femur on fracture location.
Arch Orthop Trauma Surg. 2015 Nov;135(11):1485-90. doi: 10.1007/s00402-015-2297-4. Epub 2015 Aug 19.
8
The fracture sites of atypical femoral fractures are associated with the weight-bearing lower limb alignment.
Bone. 2014 Sep;66:105-10. doi: 10.1016/j.bone.2014.06.008. Epub 2014 Jun 14.

引用本文的文献

本文引用的文献

1
Surgical outcomes of intramedullary nailing for diaphyseal atypical femur fractures: is it safe to modify a nail entry in bowed femur?
Arch Orthop Trauma Surg. 2017 Nov;137(11):1515-1522. doi: 10.1007/s00402-017-2764-1. Epub 2017 Aug 2.
2
Factors affecting fracture location in atypical femoral fractures: A cross-sectional study with 147 patients.
Injury. 2017 Jul;48(7):1570-1574. doi: 10.1016/j.injury.2017.05.033. Epub 2017 May 25.
3
Intramedullary Nailing for Atypical Femoral Fracture with Excessive Anterolateral Bowing.
J Bone Joint Surg Am. 2017 May 3;99(9):726-735. doi: 10.2106/JBJS.16.00760.
4
Location of fractures and the characteristics of patients with atypical femoral fractures: analyses of 38 Japanese cases.
J Bone Miner Metab. 2017 Mar;35(2):209-214. doi: 10.1007/s00774-016-0747-x. Epub 2016 Mar 29.
5
Atypical fractures of the femur: effect of anterolateral bowing of the femur on fracture location.
Arch Orthop Trauma Surg. 2015 Nov;135(11):1485-90. doi: 10.1007/s00402-015-2297-4. Epub 2015 Aug 19.
6
Atypical Fractures are Mainly Subtrochanteric in Singapore and Diaphyseal in Sweden: A Cross-Sectional Study.
J Bone Miner Res. 2015 Nov;30(11):2127-32. doi: 10.1002/jbmr.2547. Epub 2015 Jun 15.
9
Low-energy diaphyseal femoral fractures associated with bisphosphonate use and severe curved femur: a case series.
J Bone Miner Metab. 2012 Sep;30(5):561-7. doi: 10.1007/s00774-012-0358-0. Epub 2012 May 19.
10
Low-energy femoral shaft fractures associated with alendronate use.
J Orthop Trauma. 2008 May-Jun;22(5):346-50. doi: 10.1097/BOT.0b013e318172841c.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验