GRC 24, Handicap Moteur et Cognitif et Réadaptation, Sorbonne Université, Paris, France.
GRC 24, Handicap Moteur et Cognitif et Réadaptation, Sorbonne Université, Paris, France; Centre d'Etudes en Santé des Populations, INSERM U1018, Paris, France.
Handb Clin Neurol. 2020;173:265-304. doi: 10.1016/B978-0-444-64150-2.00023-X.
This chapter proposes a review of neuropsychologic and behavior findings in pediatric pathologies of the cerebellum, including cerebellar malformations, pediatric ataxias, cerebellar tumors, and other acquired cerebellar injuries during childhood. The chapter also contains reviews of the cerebellar mutism/posterior fossa syndrome, reported cognitive associations with the development of the cerebellum in typically developing children and subjects born preterm, and the role of the cerebellum in neurodevelopmental disorders such as autism spectrum disorders and developmental dyslexia. Cognitive findings in pediatric cerebellar disorders are considered in the context of known cerebellocerebral connections, internal cellular organization of the cerebellum, the idea of a universal cerebellar transform and computational internal models, and the role of the cerebellum in specific cognitive and motor functions, such as working memory, language, timing, or control of eye movements. The chapter closes with a discussion of the strengths and weaknesses of the cognitive affective syndrome as it has been described in children and some conclusions and perspectives.
这一章提出了对小儿小脑病理学的神经心理和行为研究结果的综述,包括小脑畸形、小儿共济失调、小脑肿瘤和儿童期其他获得性小脑损伤。该章还对小脑缄默症/后颅窝综合征、在正常发育的儿童和早产儿中与小脑发育相关的认知关联、以及小脑在神经发育障碍(如自闭症谱系障碍和发育性阅读障碍)中的作用进行了综述。在考虑小儿小脑疾病的认知发现时,我们考虑了已知的小脑-大脑连接、小脑的内部细胞组织、通用小脑变换和计算内部模型的概念,以及小脑在特定认知和运动功能(如工作记忆、语言、时间或眼球运动控制)中的作用。最后,讨论了在儿童中描述的认知情感综合征的优缺点,并得出了一些结论和观点。