Supramolecular Chemistry of Titanium Oxide Clusters.

Titanium oxide clusters (TOCs) have been emerging as a new type of inorganic molecular entities of supramolecular chemistry. Herein, a perspective on the structures and functionalities of TOCs over the past three decades is given and the paramount roles of TOCs in serving supramolecular chemistry are demonstrated. Four types of supramolecular assemblies based on TOCs are reviewed, namely, TOC hosts for ion inclusion, mechanically interlocked molecular systems built from cyclic TOCs, reactivities of surface sites toward ligand exchange, and hierarchical structures of TOCs. The principles and advantages of TOCs toward each application are fully discussed, along with structural analyses. Following this path, more functional TOC-based supramolecular systems may be designed and synthesized in the future, which, in turn, will certainly enhance research into both supramolecular and coordination chemistry of titanium.