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避孕研究与开发的进展。

Advances in contraception research and development.

机构信息

Division of Family Planning Services and Research, Department of Obstetrics and Gynecology, Stanford University, School of Medicine, Stanford, California, USA.

出版信息

Curr Opin Obstet Gynecol. 2020 Dec;32(6):393-398. doi: 10.1097/GCO.0000000000000666.

Abstract

PURPOSE OF REVIEW

In the past few years, there have been great advances in contraceptive technology and development. Here we review advances in contraception over the past two years including new medications, and technologies.

RECENT FINDINGS

Contraception must be discussed within the context of individual goals and context. New contraceptive options approved by the FDA in the past two years include a year-long vaginal ring, a progestin-only pill that is as effective as combined oral contraceptive pills, a new hormonal patch and a vaginal gel that may also help prevent sexually transmitted infections.There are still areas of contraceptive research that are very much unknown including biomarkers of contraceptive efficacy or side effects, how individuals or groups metabolize contraception, initiation around reproductive life events or the discontinuation of other methods.

SUMMARY

There have been many new contraceptives developed over the past few years to address challenges of existing contraception and create new methods; yet, there remain many unanswered questions in contraceptive research. Contraceptive technology has far-reaching consequences, and independent of technology itself, represents a great opportunity for truly personalized medicine.

摘要

目的综述

在过去的几年中,避孕技术和发展取得了重大进展。在这里,我们回顾了过去两年中避孕方面的进展,包括新的药物和技术。

最近的发现

避孕必须在个人目标和背景的背景下进行讨论。过去两年中获得 FDA 批准的新避孕选择包括一种可使用一年的阴道环、一种与复方口服避孕药同样有效的孕激素避孕药、一种新的激素贴剂和一种可能有助于预防性传播感染的阴道凝胶。避孕研究仍有许多未知领域,包括避孕效果或副作用的生物标志物、个体或群体如何代谢避孕措施、生殖生命事件前后的起始以及其他方法的停药。

总结

在过去的几年中,已经开发出许多新的避孕方法来应对现有避孕方法的挑战并创造新的方法;然而,避孕研究仍有许多悬而未决的问题。避孕技术具有深远的影响,并且独立于技术本身,为真正的个性化医疗提供了巨大的机会。

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