18F-FDG PET/CT 评估移植肾来源的恶性外周神经鞘瘤。

Malignant Peripheral Nerve Sheath Tumor Arising From Transplanted Kidney Assessed by 18F-FDG PET/CT.

机构信息

From the PET-CT/MRI Center and Molecular Imaging Center, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.

出版信息

Clin Nucl Med. 2020 Nov;45(11):905-907. doi: 10.1097/RLU.0000000000003273.

Abstract

Malignant peripheral nerve sheath tumor (MPNST) originates from Schwann cells or pluripotent perineural cells, which is an extremely rare tumor that occurs in the kidney. We report a case of MPNST in transplanted kidney that was diagnosed in a 32-year-old man with a history of kidney transplantation. Contrast-enhanced MRI and F-FDG PET/CT features of MPNST are described, which can accurately discriminate MPNST from infection and benign tumors. These features could potentially provide valuable information to distinguish it from other renal malignancies. F-FDG PET/CT may be a useful tool for the primary diagnosis and the initial staging of MPNST.

摘要

恶性外周神经鞘瘤（MPNST）起源于许旺细胞或多能周围神经细胞，是一种极为罕见的发生于肾脏的肿瘤。我们报告了一例移植肾中的 MPNST，患者为 32 岁男性，有肾移植病史。本文描述了 MPNST 的 MRI 增强表现和 F-FDG PET/CT 特征，这些特征可以准确地区分 MPNST 与感染和良性肿瘤。这些特征可能为鉴别其他肾恶性肿瘤提供有价值的信息。F-FDG PET/CT 可能是 MPNST 原发诊断和初始分期的有用工具。