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赫尔辛基在新冠疫情期间对创伤性脑损伤和颅内动脉瘤性蛛网膜下腔出血的强化治疗。

Intensive care of traumatic brain injury and aneurysmal subarachnoid hemorrhage in Helsinki during the Covid-19 pandemic.

机构信息

Division of Anaesthesiology, Department of Anaesthesiology, Intensive Care and Pain Medicine, Helsinki University Hospital, Topeliuksenkatu 5, PO BOX 266, 00029 HUS, Helsinki, Finland.

Department of Neurosurgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

出版信息

Acta Neurochir (Wien). 2020 Nov;162(11):2715-2724. doi: 10.1007/s00701-020-04583-4. Epub 2020 Sep 24.

Abstract

BACKGROUND

To ensure adequate intensive care unit (ICU) capacity for SARS-CoV-2 patients, elective neurosurgery and neurosurgical ICU capacity were reduced. Further, the Finnish government enforced strict restrictions to reduce the spread. Our objective was to assess changes in ICU admissions and prognosis of traumatic brain injury (TBI) and aneurysmal subarachnoid hemorrhage (SAH) during the Covid-19 pandemic.

METHODS

Retrospective review of all consecutive patients with TBI and aneurysmal SAH admitted to the neurosurgical ICU in Helsinki from January to May of 2019 and the same months of 2020. The pre-pandemic time was defined as weeks 1-11, and the pandemic time was defined as weeks 12-22. The number of admissions and standardized mortality rates (SMRs) were compared to assess the effect of the Covid-19 pandemic on these. Standardized mortality rates were adjusted for case mix.

RESULTS

Two hundred twenty-four patients were included (TBI n = 123, SAH n = 101). There were no notable differences in case mix between TBI and SAH patients admitted during the Covid-19 pandemic compared with before the pandemic. No notable difference in TBI or SAH ICU admissions during the pandemic was noted in comparison with early 2020 or 2019. SMRs were no higher during the pandemic than before.

CONCLUSION

In the area of Helsinki, Finland, there were no changes in the number of ICU admissions or in prognosis of patients with TBI or SAH during the Covid-19 pandemic.

摘要

背景

为确保有足够的重症监护病房(ICU)容量来收治 SARS-CoV-2 患者,神经外科和神经外科 ICU 的择期手术能力有所降低。此外,芬兰政府实施了严格的限制措施以减少病毒传播。我们的目的是评估在 COVID-19 大流行期间,创伤性脑损伤(TBI)和颅内动脉瘤性蛛网膜下腔出血(SAH)患者 ICU 收治情况和预后的变化。

方法

回顾性分析了 2019 年 1 月至 5 月和 2020 年同期连续收治于赫尔辛基神经外科 ICU 的所有 TBI 和颅内动脉瘤性 SAH 患者。将大流行前的时间定义为第 1 周到第 11 周,大流行期间的时间定义为第 12 周到第 22 周。比较 ICU 收治人数和标准化死亡率(SMR),以评估 COVID-19 大流行对这些因素的影响。SMR 按病例组合进行调整。

结果

共纳入 224 例患者(TBI 患者 123 例,SAH 患者 101 例)。与大流行前相比,TBI 和 SAH 患者在大流行期间的病例组合无明显差异。与 2020 年初或 2019 年相比,大流行期间 TBI 或 SAH 的 ICU 收治人数无明显差异。SMR 在大流行期间并未升高。

结论

在芬兰赫尔辛基地区,COVID-19 大流行期间 TBI 或 SAH 患者的 ICU 收治人数或预后均无变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/344e/7550377/dc82039ef08e/701_2020_4583_Fig1_HTML.jpg

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