From the Department of Surgery (A.C.S., A.V.G., F.M.P., K.B.P., R.A.L., E.M.C., J.J.C., E.E.M., C.C.B.), Denver Health Medical Center, Denver, Colorado; Department of Anesthesia (A.W.), Brigham and Women's Hospital, Harvard University, Boston, Massachussets; and Department of Surgery (A.E.R.), University of Colorado, Aurora, Colorado.
J Trauma Acute Care Surg. 2021 Jan 1;90(1):137-142. doi: 10.1097/TA.0000000000002947.
Use of the focused assessment with sonography for trauma (FAST) examination in patients with pelvic fractures has been reported as unreliable. We hypothesized that FAST is a reliable method for detecting clinically significant intra-abdominal hemorrhage in patients with pelvic fractures.
All patients with pelvic fractures over a 10-year period were reviewed at a Level I trauma center. The predictive ability of FAST was assessed by calculating the sensitivity, specificity, positive predictive value and negative predictive value against the criterion standard of either computed tomography (CT) or laparotomy findings. The FAST examination was considered "false negative" if findings at laparotomy indicated traumatic intra-abdominal hemorrhage. Likewise, the FAST examination was considered "false positive" if either CT or findings at laparotomy indicated no intra-abdominal hemorrhage. Hemodynamic instability scores were calculated for all patients.
There were 1,456 patients with pelvic fractures and an initial FAST reviewed; 1,219 (83.7%) underwent FAST and either CT or operative exploration. Median age was 43 years (interquartile range, 26-56 years) and mean Injury Severity Score was 18.5 ± 12.3. The sensitivity and specificity for FAST in this group of patients with pelvic fracture was 85.4% and 98.1%, respectively. The positive predictive value and negative predictive value were 78.4% and 98.8%, respectively. Of 21 patients with a false-positive FAST, 15 (71.4%) were confirmed with a negative CT scan, and 6 (28.6%) underwent laparotomy without findings of intra-abdominal hemorrhage. Of 13 patients with a false-negative FAST, all were identified with positive findings at the time of laparotomy. The specificity of the FAST examination remained high regardless of hemodynamic instability score grade.
The false positive rate of FAST examination for intra-abdominal hemorrhage is 1.1%. These data suggest that a positive FAST in this clinical scenario should be considered to represent intra-abdominal fluid. This series contradicts prior reports that FAST is unreliable in patients with pelvic fracture.
Diagnostic, level III.
已有报道称,在骨盆骨折患者中使用创伤重点超声评估(FAST)检查结果不可靠。我们假设 FAST 是一种可靠的方法,可用于检测骨盆骨折患者中具有临床意义的腹腔内出血。
对 10 年间在一家一级创伤中心就诊的所有骨盆骨折患者进行了回顾性研究。通过计算敏感度、特异度、阳性预测值和阴性预测值来评估 FAST 的预测能力,并将其与 CT 或剖腹探查结果的标准进行对比。如果剖腹探查结果提示有创伤性腹腔内出血,则将 FAST 检查结果视为“假阴性”。同样,如果 CT 或剖腹探查结果提示无腹腔内出血,则将 FAST 检查结果视为“假阳性”。对所有患者计算血流动力学不稳定评分。
共 1456 例骨盆骨折患者接受了初始 FAST 检查,其中 1219 例(83.7%)患者进行了 FAST 检查并接受了 CT 或手术探查。患者中位年龄为 43 岁(四分位间距,26-56 岁),平均损伤严重度评分(ISS)为 18.5±12.3。在这组骨盆骨折患者中,FAST 的敏感度和特异度分别为 85.4%和 98.1%。阳性预测值和阴性预测值分别为 78.4%和 98.8%。21 例 FAST 假阳性患者中,15 例(71.4%)患者 CT 扫描结果为阴性,6 例(28.6%)患者接受了剖腹探查但未见腹腔内出血。13 例 FAST 假阴性患者在剖腹探查时均发现阳性结果。无论血流动力学不稳定评分等级如何,FAST 检查的特异度均保持较高水平。
FAST 检查腹腔内出血的假阳性率为 1.1%。这些数据表明,在这种临床情况下,如果 FAST 检查结果为阳性,应考虑存在腹腔内液体。本系列研究结果与先前报道的 FAST 在骨盆骨折患者中不可靠的结论相悖。
诊断性,III 级。