Delayed SARS-COV-2 leukoencephalopathy without Severe Hypoxia.

• A patient developed encephalopathy two months after a mild case of COVID-19. • MRI Brain demonstrated extensive white matter lesions juxtacortically and subcortically. • Workup for infectious, paraneoplastic, toxic process was negative. • MBP was elevated, prompting diagnosis of post-infectious ADEM following COVID-19. • COVID-19 patients without hypoxia may have post-infectious leukoencephalopathy.