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应用网膜游离皮瓣治疗慢性前颅底感染。

Use of the Omental Free Flap for Treatment of Chronic Anterior Skull Base Infections.

作者信息

Kokosis George, Vorstenbosch Joshua, Lombardi Arianna, Shamsunder Meghana G, Mehrara Babak, Hespe Geoffrey E, Wang Laura, Brennan Cameron W, Ganly Ian, Matros Evan

机构信息

Division of Plastic and Reconstructive Surgery, Memorial Sloan Kettering, New York, N.Y.

Division of Plastic and Reconstructive Surgery, University of Michigan, Ann Arbor, Mich.

出版信息

Plast Reconstr Surg Glob Open. 2020 Aug 11;8(8):e2988. doi: 10.1097/GOX.0000000000002988. eCollection 2020 Aug.

Abstract

Chronic complications following anterior cranial fossa tumor extirpation, such as cerebrospinal fluid leak, meningitis, mucocele, pneumocephalus, and abscess, negatively impact patient quality of life. Robust vascularized tissue is generally required to adequately reconstruct and obliterate this complex geometric space. The aim of this study was to describe outcomes and advantages of the omental flap for these defects. Following institutional review board approval, a prospective, reconstructive database was reviewed from 2011 to 2020. Four patients with chronic anterior skull base complications treated with omental flap reconstruction were identified, with chart reviews performed. Median time from the index operation until the complication ultimately required a free omental transfer was 7.3 years. All patients underwent adjuvant radiation with the indications for surgery, including cerebral abscess, recurrent meningitis, osteomyelitis, and pneumocephalus. All free flaps survived without any need for revision. There were no donor site complications. One patient had delayed healing at an adjacent nasal wound that healed secondarily. At a median follow-up of 19.4 months, none of the patients had recurrent infections. The omental free flap has a number of properties, which make it ideally suitable for anterior skull base defects. Its malleable nature combined with the presence of multiple vascular arcades enable flexibility in flap design to contour to the crevices of 3-dimensional skull base defects. Although other free flaps are available to the plastic surgeon, the versatility and reliability of the omentum make it a first-line consideration for anterior skull base reconstruction.

摘要

前颅窝肿瘤切除术后的慢性并发症,如脑脊液漏、脑膜炎、黏液囊肿、气颅和脓肿,会对患者的生活质量产生负面影响。通常需要强健的带血管组织来充分重建和封闭这个复杂的几何空间。本研究的目的是描述大网膜瓣修复这些缺损的效果和优势。经机构审查委员会批准,对2011年至2020年的前瞻性重建数据库进行了回顾。确定了4例接受大网膜瓣重建治疗慢性前颅底并发症的患者,并进行了病历回顾。从初次手术到并发症最终需要游离大网膜转移的中位时间为7.3年。所有患者均因手术指征接受了辅助放疗,手术指征包括脑脓肿、复发性脑膜炎、骨髓炎和气颅。所有游离瓣均存活,无需任何修复。没有供区并发症。1例患者相邻鼻伤口愈合延迟,随后二期愈合。中位随访19.4个月时,所有患者均无反复感染。大网膜游离瓣具有多种特性,使其非常适合修复前颅底缺损。其可塑性与多个血管弓的存在相结合,使瓣设计具有灵活性,能够贴合三维颅底缺损的缝隙。虽然整形外科医生还有其他游离瓣可供选择,但大网膜的多功能性和可靠性使其成为前颅底重建的一线选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b068/7489647/f92ed76ba3ff/gox-8-e2988-g001.jpg

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