Nakazawa M, Sugimoto C, Isayama Y, Kashiwazaki M
Vet Microbiol. 1987 Apr;13(4):291-300. doi: 10.1016/0378-1135(87)90060-5.
A total of 567 strains of Escherichia coli were isolated from piglets with neonatal diarrhea (ND) or post-weaning diarrhea (PWD) in Japan. They were investigated for enterotoxigenicity and possession of adhesins and O antigens. There were clear differences between the strains of ND origin and those of PWD origin in the occurrence of enterotoxigenic E. coli (ETEC) strains, type of enterotoxin and frequency of adhesins: ETEC was found in 77 (25.7%) of 300 strains of ND origin and in 137 (51.3%) of 267 strains of PWD origin. ETEC strains producing heat-labile enterotoxin (LT) or heat-stable enterotoxin (STa), alone or in combination were evenly distributed among the strains of PWD origin. In contrast most of the ETEC strains of ND origin produced LT alone. Adhesins appeared in 42 (54.5%) of 77 ETEC strains of ND origin and in 36 (26.3%) of 137 ETEC strains of PWD origin. Adhesins were less common in ETEC strains of PWD origin than in those of ND origin. Some K99-positive ETEC strains of PWD origin produced both LT and STa. There was a similarity in the distribution of O antigens, particularly O149 and O157, between the strains of ND origin and those of PWD origin.
从日本患有新生仔猪腹泻（ND）或断奶后腹泻（PWD）的仔猪中总共分离出567株大肠杆菌。对它们进行了产肠毒素能力、黏附素和O抗原的检测。源于ND的菌株和源于PWD的菌株在产肠毒素大肠杆菌（ETEC）菌株的发生率、肠毒素类型和黏附素频率方面存在明显差异：在300株源于ND的菌株中，有77株（25.7%）检测到ETEC，而在267株源于PWD的菌株中，有137株（51.3%）检测到ETEC。单独产生热不稳定肠毒素（LT）或热稳定肠毒素（STa）或两者兼有的ETEC菌株在源于PWD的菌株中分布均匀。相比之下，大多数源于ND的ETEC菌株仅产生LT。黏附素出现在77株源于ND的ETEC菌株中的42株（54.5%）以及137株源于PWD的ETEC菌株中的36株（26.3%）。源于PWD的ETEC菌株中的黏附素比源于ND的ETEC菌株中的黏附素少见。一些源于PWD的K99阳性ETEC菌株同时产生LT和STa。源于ND的菌株和源于PWD的菌株在O抗原的分布上存在相似性，尤其是O149和O157。
