Departments of Surgery.
Department of Surgery, King Faisal Specialist Hospital & Research Centre, KSA, Jeddah, Saudi Arabia.
J Pediatr Hematol Oncol. 2021 Jan;43(1):e33-e36. doi: 10.1097/MPH.0000000000001960.
Hemophiliac patients and their families have social pressure to undergo circumcision, despite the potential complications. The objective of this study was to report our experience in the circumcision of hemophilia patients.
We included 35 patients with hemophilia who had circumcision in 3 centers from January 2010 to August 2019. Their age ranged between 0.3 months and 8 years. Hemophilia a was classified as mild (n=3), moderate (n=4), and severe (n=28). Patients received 2 doses of factor VIII concentrate 50μ/kg, 1 hour before the procedure and 12 hours after it.
Four neonates were diagnosed with hemophilia after circumcision because of prolonged bleeding. Two patients with severe hemophilia A had bleeding after hospital discharge (6.5%). They received additional factor concentrate, and 1 patient had an extra stitch. Two patients had wound gaping (6.5%), and 1 patient had a wound infection (3.2%).
Hemophilia is not an absolute contraindication for circumcision. Circumcision of hemophilic children should be performed under appropriate conditions in hemophilia centers. Bleeding is not frequent but could be serious.
尽管存在潜在并发症,血友病患者及其家属仍面临进行割礼的社会压力。本研究旨在报告我们在血友病患者割礼方面的经验。
我们纳入了 2010 年 1 月至 2019 年 8 月在 3 个中心接受割礼的 35 例血友病患者。其年龄在 0.3 个月至 8 岁之间。血友病 A 分为轻度(n=3)、中度(n=4)和重度(n=28)。患者在术前 1 小时和术后 12 小时接受 2 剂 50μ/kg 的因子 VIII 浓缩物。
4 例新生儿在割礼后因持续出血而被诊断为血友病。2 例重度血友病 A 患者在出院后出现出血(6.5%)。他们接受了额外的因子浓缩物治疗,其中 1 例需要额外缝针。2 例患者出现伤口裂开(6.5%),1 例患者出现伤口感染(3.2%)。
血友病并不是割礼的绝对禁忌证。应在血友病中心的适当条件下对血友病儿童进行割礼。出血并不常见,但可能很严重。