Bozkurt Hilmi, Ölmez Tolga, Bulut Can İbrahim, Sert Özlem Zeliha, Keklikkıran Zeynep Zehra, Karaköse Erdal, Senger Aziz Serkan, Akbulut Sabiye, Polat Erdal, Duman Mustafa
Gastrointestinal Surgery Department, Kartal Koşuyolu Training and Research Hospital, Istanbul, Turkey.
Gastroenterology Department, Kartal Koşuyolu Training and Research Hospital, Istanbul, Turkey.
Prz Gastroenterol. 2020;15(3):234-240. doi: 10.5114/pg.2019.88622. Epub 2019 Oct 9.
In July 2012, the Japan Gastroenterological Endoscopy Society updated their guidelines on gastroenterological endoscopy in patients undergoing antithrombotic therapy, although the safety of endoscopic procedures in patients receiving antithrombotic drugs has yet to be sufficiently studied.
This study evaluates the safety of upper gastroenterological endoscopic biopsy in patients receiving antithrombotic drugs. We evaluated the prospective observational safety of endoscopic biopsy performed in the endoscopy unit of our patients using antithrombotic drugs.
Oesophagogastroduodenoscopies (OGD) and biopsies performed at a single endoscopy unit between July 2018 and February 2019 were examined in this prospective observational study. Patients receiving antithrombotic drugs due to cardiovascular and neurological reasons, who underwent an endoscopic mucosal biopsy for diagnostic purposes, were included in the study.
The study was completed with 166 patients who underwent an endoscopic biopsy, from whom a total of 327 biopsies taken. The patients were examined in two groups: those "receiving antithrombotic drugs" and those who had "stopped taking antithrombotic drugs". There was no statistically significant difference between the two groups with respect to bleeding.
This prospective observational study showed that performing an endoscopic biopsy without the cessation of antithrombotic drugs does not increase bleeding risk. Low-risk procedures, such as endoscopic mucosal biopsies, can be performed confidently by experienced endoscopists.
2012年7月，日本胃肠内镜学会更新了接受抗血栓治疗患者的胃肠内镜检查指南，尽管接受抗血栓药物治疗的患者进行内镜检查的安全性尚未得到充分研究。
本研究评估接受抗血栓药物治疗的患者进行上消化道内镜活检的安全性。我们评估了在我们医院使用抗血栓药物的患者在内镜科进行内镜活检的前瞻性观察安全性。
在这项前瞻性观察研究中，对2018年7月至2019年2月在单一内镜科进行的食管胃十二指肠镜检查（OGD）和活检进行了检查。因心血管和神经原因接受抗血栓药物治疗且为诊断目的进行内镜黏膜活检的患者纳入研究。
该研究共纳入166例行内镜活检的患者，共进行了327次活检。患者分为两组：“接受抗血栓药物治疗”组和“已停用抗血栓药物”组。两组在出血方面无统计学显著差异。
这项前瞻性观察研究表明，在不停用抗血栓药物的情况下进行内镜活检不会增加出血风险。经验丰富的内镜医师可以放心地进行低风险操作，如内镜黏膜活检。
