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性别对沙特阿拉伯利雅得一家三级医疗医院ST段抬高型心肌梗死治疗结果的影响。

Effect of Gender on the Outcomes of ST-Elevation Myocardial Infarction at a Tertiary Care Hospital in Riyadh, Saudi Arabia.

作者信息

Alharbi Mohammed S, Alanazi Bander K, Alquhays Ibrahim A, Alhamied Nawaf A, Al Shimemeri Abdullah

机构信息

Medicine, Qassim University, Buraiydah, SAU.

Medicine, King Faisal University, Al Ahsa, SAU.

出版信息

Cureus. 2020 Aug 29;12(8):e10118. doi: 10.7759/cureus.10118.

DOI:10.7759/cureus.10118
PMID:33005534
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7523745/
Abstract

Objective This study aimed to evaluate the impact of gender on the outcomes among ST elevation myocardial infarction patients at King Abdulaziz Medical City in Riyadh, Saudi Arabia. Methods This retrospective study analyzed the data of 900 patients (770 males and 130 females) admitted between January 2016 and December 2018 diagnosed with ST-elevation myocardial infarction (STEMI). We recorded the baseline characteristics, comorbidities, treatment, complications, and mortality for all patients, and compared these data between female and male patients. Results The baseline characteristics: BMI and age were higher in females and were statistically significant (p = 0.0001). We found a higher incidence of heart failure in females than in males which was statistically significant (p = 0.0010). In addition, the mortality rate was higher in female than in male patients, although this difference was not statistically significant (p = 0.3850). Conclusion In conclusion, despite the advances in the technology and the use of novel reperfusion therapies females were associated with poorer outcomes after adjustment of the baseline characteristics and risk factors. In other words, heart failure, mitral regurgitation, and arrhythmias were higher in females with significant p values.

摘要

目的 本研究旨在评估性别对沙特阿拉伯利雅得阿卜杜勒阿齐兹国王医疗城ST段抬高型心肌梗死患者预后的影响。方法 这项回顾性研究分析了2016年1月至2018年12月期间收治的900例诊断为ST段抬高型心肌梗死(STEMI)患者的数据(770例男性和130例女性)。我们记录了所有患者的基线特征、合并症、治疗情况、并发症和死亡率,并比较了女性和男性患者之间的这些数据。结果 基线特征:女性的BMI和年龄较高,且具有统计学意义(p = 0.0001)。我们发现女性心力衰竭的发生率高于男性,具有统计学意义(p = 0.0010)。此外,女性患者的死亡率高于男性患者,尽管这种差异无统计学意义(p = 0.3850)。结论 总之,尽管技术有所进步且使用了新型再灌注疗法,但在调整基线特征和危险因素后,女性患者的预后较差。换句话说,女性心力衰竭、二尖瓣反流和心律失常的发生率较高,p值具有显著性。

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本文引用的文献

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ST-elevation myocardial infarction in a real world population - An observational retrospective study with a sex perspective.真实世界人群中的 ST 段抬高型心肌梗死——一项具有性别视角的观察性回顾性研究。
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Is female gender associated with worse outcome after ST elevation myocardial infarction?女性性别与ST段抬高型心肌梗死预后较差是否相关?
Indian Heart J. 2017 Apr;69 Suppl 1(Suppl 1):S28-S33. doi: 10.1016/j.ihj.2016.12.003. Epub 2016 Dec 14.
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Risk Factors for Myocardial Infarction in Women and Men: A Review of the Current Literature.男性和女性心肌梗死的危险因素:当前文献综述
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Gender differences in pre-event health status of young patients with acute myocardial infarction: A VIRGO study analysis.急性心肌梗死年轻患者事件前健康状况的性别差异:VIRGO研究分析
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Gender, age and risk of ST segment elevation myocardial infarction.性别、年龄与 ST 段抬高型心肌梗死风险。
Eur J Clin Invest. 2014 Oct;44(10):902-9. doi: 10.1111/eci.12321.
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Eleven-year trends in gender differences of treatments and mortality in ST-elevation acute myocardial infarction in northern Italy, 2000 to 2010.意大利北部 2000 至 2010 年 ST 段抬高急性心肌梗死治疗和死亡率的性别差异十一年趋势
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Gender differences in presentation, management and inhospital outcome in patients with ST-segment elevation myocardial infarction: data from 5000 patients included in the ORBI prospective French regional registry.ST段抬高型心肌梗死患者在临床表现、治疗及住院结局方面的性别差异:来自法国ORBI前瞻性地区注册研究中5000例患者的数据
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