Postgraduate Program in Food, Nutrition and Health, Federal University of Rio Grande do Sul, UFRGS, Porto Alegre, Rio Grande do Sul, Brazil.
Postgraduate Graduate Program in Nutrition Sciences, Federal University of Health Science of Porto Alegre, UFCSPA, Porto Alegre, Rio Grande do Sul, Brazil.
Obes Rev. 2021 Mar;22(3):e13143. doi: 10.1111/obr.13143. Epub 2020 Oct 2.
A systematic review with meta-analysis (MA) was conducted to synthesize the effectiveness of nutrition intervention strategies for managing overweight and obesity in the adult population attending primary health care. Relevant articles were searched in the PubMed, Embase, Web of Science, Cochrane and LILACS databases from inception to January 2020. Seventy studies were identified: 45 randomized controlled trials (RCTs) and 25 uncontrolled before-after studies (UBAs). The MA of nutritional intervention revealed a reduced average estimate of the effect on weight in RCTs (weighted mean differences [WMD] = -1.80 kg, 95% confidence interval [CI], -2.40 to -1.19), BMI (WMD = -0.80 kg/m , 95% CI, -1.11 to -0.49), and WC (WMD = -2.28 cm, 95% CI, -3.06 to -1.49); and for UBAs showed reductions in weight (WMD = -4.17 kg; 95% CI, -5.18 to -1.70), BMI (WMD = -1.26 kg/m ; 95% CI, -1.81 to -0.72) and (WMD = -2.90 cm; 95%CI, -4.21 to -1.59). There was no association between treatment effect and follow-up for both designs. Nutritional interventions alone yielded a higher but nonsignificant average reduction on weight when compared with combined components intervention. Interventions delivered through individual or group sessions showed a similar positive effect on weight decrease. The dietary prescription approach yielded a greater effect on weight loss than did the behavioural approaches but only in UBA studies.
系统评价和荟萃分析(MA)表明,营养干预策略对管理初级保健机构成年超重和肥胖人群有效。从建库到 2020 年 1 月,我们在 PubMed、Embase、Web of Science、Cochrane 和 LILACS 数据库中检索了相关文章。共确定了 70 项研究:45 项随机对照试验(RCT)和 25 项非对照前后研究(UBAs)。营养干预的 MA 显示 RCT 中体重的平均效应降低(加权均数差 [WMD] = -1.80kg,95%置信区间 [CI],-2.40 至 -1.19),BMI(WMD = -0.80kg/m ,95% CI,-1.11 至 -0.49)和 WC(WMD = -2.28cm,95% CI,-3.06 至 -1.49);UBAs 显示体重降低(WMD = -4.17kg;95% CI,-5.18 至 -1.70)、BMI(WMD = -1.26kg/m ;95% CI,-1.81 至 -0.72)和 WC(WMD = -2.90cm;95%CI,-4.21 至 -1.59)。两种设计的治疗效果与随访均无相关性。与联合成分干预相比,单独进行营养干预对体重的平均降低作用更高,但无统计学意义。通过个体或小组会议进行的干预对体重减轻有相似的积极影响。饮食处方方法对体重减轻的效果大于行为方法,但仅在 UBA 研究中。