Department of General Medicine, Government Medical College and Hospital, Chandigarh, India.
Department of General Medicine, Government Medical College and Hospital, Chandigarh, India
BMJ Case Rep. 2020 Oct 4;13(10):e237262. doi: 10.1136/bcr-2020-237262.
The clinical course of a 40-year-old female patient, who presented with acute febrile illness due to scrub typhus fever became complicated by seizures and posterior reversible encephalopathy syndrome (PRES), leading to a fatal outcome. She had normal blood pressure at admission; however, she later developed hypotension and shock. PRES is a syndrome of vasogenic cerebral oedema and accompanying neurological deficits resulting from the breakdown of blood-brain barrier due to high blood pressure or radical blood pressure changes. PRES is a clinico-radiographic diagnosis of heterogeneous aetiologies and is rare in the context of infections. Although there are many neurological manifestations in scrub typhus, to the best of our knowledge, PRES has never been reported.
一位 40 岁女性患者因恙虫病导致急性发热性疾病，病情变得复杂，出现癫痫发作和后部可逆性脑病综合征（PRES），最终导致死亡。患者入院时血压正常；但后来出现低血压和休克。 PRES 是一种由于血脑屏障因高血压或血压急剧变化而破裂导致的血管源性脑水肿和伴随的神经功能缺损的综合征。 PRES 是一种临床放射学诊断，病因多样，在感染的情况下很少见。尽管恙虫病有许多神经表现，但据我们所知， PRES 从未被报道过。
