Gabriel Rami S, Boisvert Chantal J, Mehta Mitul C
School of Medicine, University of California, Irvine, California, USA.
Department of Ophthalmology, Duke Eye Center and Duke University Medical Center, Durham, North Carolina, USA.
Neuroophthalmology. 2020 Feb 26;44(4):213-218. doi: 10.1080/01658107.2020.1725063. eCollection 2020.
Vitreopapillary traction (VPT) syndrome is a potentially visually significant disorder of the vitreopapillary interface characterised by an incomplete posterior vitreous detachment with the persistently adherent vitreous exerting tractional pull on the optic disc and resulting in morphologic alterations and a consequent decline of visual function. It is most commonly unilateral but bilateral reports have also been described. The cause of the condition may be unknown or idiopathic, although the histology of traction shows proliferation of fibrous astrocytes, myofibroblasts, fibrocytes, and retinal pigment epithelial cells. It is theorised that VPT may induce a congested optic disc with neuronal dysfunction as well as decreased prelaminar flow. The present study reviews and summarises the features, diagnosis, and management of VPT.
玻璃体视乳头牵引(VPT)综合征是一种对视功能有潜在重要影响的玻璃体视乳头界面疾病,其特征为不完全性玻璃体后脱离,持续附着的玻璃体对视盘施加牵引拉力,导致形态学改变及视功能随之下降。该病最常见为单侧性,但也有双侧病例的报道。尽管牵引的组织学表现为纤维性星形胶质细胞、肌成纤维细胞、纤维细胞和视网膜色素上皮细胞增生,但该病的病因可能不明或为特发性。理论上,VPT可能导致视盘充血、神经元功能障碍以及筛板前血流减少。本研究回顾并总结了VPT的特征、诊断及治疗。