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冷冻手术与三氯乙酸化学烧灼治疗肥厚性鼻甲的比较研究

Cryosurgery Vs Trichloroacetic Acid Chemical Cautery for the Treatment of Hypertrophied Nasal Turbinate: A Comparative Study.

作者信息

Satpute Satish S, Joshi Samir V, Arora Ripudaman, Prabha Neel, Keche Prashant, Nagarkar Nitin M

机构信息

Department of Otorhinolaryngology and Head and Neck Surgery, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India.

Department of Otorhinolaryngology and Head and Neck Surgery, BJ Government Medical College, Pune, India.

出版信息

Iran J Otorhinolaryngol. 2020 Sep;32(112):303-309. doi: 10.22038/ijorl.2019.39039.2293.

DOI:10.22038/ijorl.2019.39039.2293
PMID:33014907
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7515624/
Abstract

INTRODUCTION

The Study Aimed To Compare The Results of Cryosurgery With Trichloroacetic Acid Chemical (TCA) Cautery For The Treatment of Hypertrophied Nasal Turbinates.

MATERIALS AND METHODS

This was a prospective study of 70 patients with nasal obstruction due to hypertrophied nasal turbinates who were randomly divided in 2 groups of 35 each. In group 1, patients underwent inferior nasal turbinate reduction by cryosurgery and in group 2 patients with cautery by 50 % TCA. The patients were evaluated using SNOT-20 score pre and postoperatively on 6th month.

RESULTS

Significant improvement in symptoms was seen in 28 patients (80 %) in group 1 and in 10 patients (28.57%) in group 2..Improvement in average SNOT Score after cauterization of hypertrophied nasal turbinates by cryosurgery was from 55(severe) to 16(mild) and by TCA was from 54(severe) to 32(mod) in 6 months and this was statistically significant (P<0.001). Complications like bleeding, scarring, infection and adhesion formation were more with TCA than that of cryosurgery group and among these complications scarring was statistically significant (P =0.003).

CONCLUSION

The use of cryosurgical treatment for hypertrophied nasal turbinates is a safe, curative method as compared to that of TCA cautery which is less curative and with more complications.

摘要

引言

本研究旨在比较冷冻手术与三氯乙酸化学烧灼术治疗肥厚性鼻甲的效果。

材料与方法

这是一项前瞻性研究,70例因肥厚性鼻甲导致鼻塞的患者被随机分为两组,每组35例。第1组患者接受下鼻甲冷冻手术,第2组患者接受50%三氯乙酸烧灼术。在术后第6个月,使用鼻鼻窦结局测试20(SNOT-20)评分对患者进行术前和术后评估。

结果

第1组28例患者(80%)症状有显著改善,第2组10例患者(28.57%)症状有改善。冷冻手术烧灼肥厚性鼻甲后6个月,平均SNOT评分从55(重度)改善至16(轻度),三氯乙酸烧灼术则从54(重度)改善至32(中度),差异有统计学意义(P<0.001)。三氯乙酸烧灼术出现出血、瘢痕形成、感染和粘连等并发症的情况比冷冻手术组更多,其中瘢痕形成差异有统计学意义(P =0.003)。

结论

与三氯乙酸烧灼术相比,冷冻手术治疗肥厚性鼻甲是一种安全、有效的方法,三氯乙酸烧灼术疗效较差且并发症更多。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b6f/7515624/33cd97713a0c/ijo-32-303-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b6f/7515624/b05b4e9cb128/ijo-32-303-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b6f/7515624/d4ca6ef2d339/ijo-32-303-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b6f/7515624/7fe4f9f18198/ijo-32-303-g003.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b6f/7515624/fdba0d2ca07a/ijo-32-303-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b6f/7515624/33cd97713a0c/ijo-32-303-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b6f/7515624/b05b4e9cb128/ijo-32-303-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b6f/7515624/d4ca6ef2d339/ijo-32-303-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b6f/7515624/7fe4f9f18198/ijo-32-303-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b6f/7515624/dd47bb7fc0d3/ijo-32-303-g004.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b6f/7515624/33cd97713a0c/ijo-32-303-g006.jpg

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